White Sox vs. Pirates Prediction: Pittsburgh Predicted to Win Saturday's MLB Matchup [7/19/2025]

The Pittsburgh Pirates will face the Chicago White Sox in MLB action at PNC Park on Saturday, commencing at 6:40PM ET.

Mike Burrows (1-3, 4.83 ERA) will get the ball for the Pirates, while the White Sox have opted for Adrian Houser (5-2, 1.56 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Pirates as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive White Sox vs. Pirates predictions page.

Pirates vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Saturday's MLB matchup between the White Sox and Pirates 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Pirates a 58% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 62% chance of covering the run line, while the over/under total of 8 runs has a 53% chance of staying under.

White Sox vs. Pirates Odds [7/19/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Pirates
Run Line	+1.5 (-184)	-1.5 (+152)
Moneyline	+118	-135
Total	o8 (-105)	u8 (-112)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Pirates Picks and Best Bets

Our model's biggest edge in today's White Sox vs. Pirates matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

White Sox vs. Pirates Game-Day Updates and Essential Details

Saturday's MLB action between the Pirates and White Sox at PNC Park is scheduled to commence at 6:40PM ET.

• Who: Chicago White Sox vs. Pittsburgh Pirates
• Date: Saturday, July 19, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: PNC Park

Dimers.com's in-depth preview of Saturday's White Sox vs. Pirates matchup includes our prediction, picks and the latest betting odds.

Before making any White Sox vs. Pirates picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Pirates, with a 58% win probability, will likely beat the White Sox on Saturday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Pirates insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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