White Sox vs. Twins prediction: Why Minnesota is favored to win Thursday's MLB matchup [9/4/2025]

The Minnesota Twins and Chicago whitesox will meet in MLB action at Target Field on Thursday, starting at 7:40PM ET.

Taj Bradley (6-7, 4.82 ERA) will start for the Twins, pitting him against Fraser Ellard (0-2, 4.82 ERA) for the White Sox.

Based on updated simulation results, Dimers' proven MLB model predicts the Twins as the most likely winner of today's game.

For further insights into Thursday's matchup, including best bets and picks, visit our interactive White Sox vs. Twins predictions page.

Twins vs. White Sox prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the result of Thursday's MLB matchup between the White Sox and Twins 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Twins a 59% chance of beating the White Sox.

According to our model, the White Sox (+1.5) have a 59% chance of covering the run line, while the 8.5-run over/under has a 53% chance of going over.

White Sox vs. Twins odds [9/4/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Twins
Run Line	+1.5 (-160)	-1.5 (+140)
Moneyline	+130	-154
Total	o8.5 (-110)	u8.5 (-105)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Twins picks and best bets

Our model's biggest edge in today's White Sox vs. Twins matchup is on the run line.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

White Sox vs. Twins game-day updates and essential details

Thursday's MLB action between the Twins and White Sox at Target Field is scheduled to begin at 7:40PM ET.

• Who: Chicago White Sox vs. Minnesota Twins
• Date: Thursday, September 4, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Target Field

Dimers.com's in-depth preview of Thursday's White Sox vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any White Sox vs. Twins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Twins, with a 59% win probability, will likely beat the White Sox on Thursday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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