White Sox vs. Royals prediction: Kansas City predicted to win Saturday's MLB matchup [8/16/2025]

The Kansas City Royals and Chicago whitesox will lock horns in MLB action at Kauffman Stadium on Saturday, starting at 7:10PM ET.

The Royals will send Michael Lorenzen (5-8, 4.60 ERA) to the mound, up against Sean Burke (4-9, 4.26 ERA) for the White Sox.

Based on updated simulation results, Dimers' advanced MLB model predicts the Royals as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive White Sox vs. Royals predictions page.

Royals vs. White Sox prediction: Who will win, cover the run line?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's MLB matchup between the White Sox and Royals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Royals a 57% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 61% chance of covering the run line, while the 9.5-run over/under has a 54% chance of staying under.

White Sox vs. Royals odds [8/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Royals
Run Line	+1.5 (-160)	-1.5 (+135)
Moneyline	+125	-144
Total	o9.5 (-104)	u9.5 (-115)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Royals picks and best bets

Our model's biggest edge in today's White Sox vs. Royals matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

White Sox vs. Royals game-day updates and essential details

Saturday's MLB matchup between the Royals and White Sox at Kauffman Stadium is scheduled to start at 7:10PM ET.

• Who: Chicago White Sox vs. Kansas City Royals
• Date: Saturday, August 16, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Kauffman Stadium

Dimers.com's full preview of Saturday's White Sox vs. Royals matchup includes our prediction, picks and the latest betting odds.

Before making any White Sox vs. Royals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Royals, with a 57% win probability, will likely beat the White Sox on Saturday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Royals insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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