White Sox vs. Astros Prediction: Houston Predicted to Win Thursday's MLB Matchup [6/12/2025]

The Houston Astros will take on the Chicago White Sox in MLB action at Daikin Park on Thursday, beginning at 8:10PM ET.

The Astros will send Framber Valdez (6-4, 3.07 ERA) to the mound, while the White Sox have opted for Davis Martin (2-6, 3.62 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's CHI White Sox-Houston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Astros with a win probability of 72% and the White Sox with 28%."

For further insights into Thursday's matchup, including best bets and picks, visit our interactive White Sox vs. Astros predictions page.

Astros vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Thursday's MLB game between the White Sox and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Astros a 72% chance of beating the White Sox.

According to our model, the Astros (-1.5) have a 52% chance of covering the run line, while the 7.5-run over/under has a 53% chance of staying under.

White Sox vs. Astros Odds [6/12/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Astros
Run Line	+1.5 (+105)	-1.5 (-120)
Moneyline	+226	-275
Total	o7.5 (-105)	u7.5 (-112)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Astros Picks and Best Bets

Our model's strongest edge in today's White Sox vs. Astros matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

White Sox vs. Astros Game-Day Updates and Essential Details

Thursday's MLB game between the Astros and White Sox at Daikin Park is scheduled to begin at 8:10PM ET.

• Who: Chicago White Sox vs. Houston Astros
• Date: Thursday, June 12, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's comprehensive preview of Thursday's White Sox vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Houston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Astros, with a 72% win probability, will likely beat the White Sox on Thursday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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