White Sox vs. Reds Prediction: Cincinnati Predicted to Win Thursday's MLB Matchup [5/15/2025]

The Cincinnati Reds and Chicago whitesox will meet in MLB action at Great American Ball Park on Thursday, starting at 12:40PM ET.

The Reds will have Nick Martinez (1-4, 4.23 ERA) as their starting pitcher, pitting him against Bryse Wilson (0-1, 4.88 ERA) for the White Sox.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Reds as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's CHI White Sox-Cincinnati game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Reds with a win probability of 65% and the White Sox with 35%."

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive White Sox vs. Reds predictions page.

Reds vs. White Sox Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Thursday's MLB game between the White Sox and Reds 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Reds a 65% chance of defeating the White Sox.

According to our model, the White Sox (+1.5) have a 53% chance of covering the run line, while the over/under total of 9 runs has an equal 50-50 chance of hitting.

White Sox vs. Reds Odds [5/15/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	White Sox	Reds
Run Line	+1.5 (+105)	-1.5 (-115)
Moneyline	+200	-235
Total	o9 (-122)	u9 (+105)

All odds are correct at the time of publication and are subject to change.

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White Sox vs. Reds Picks and Best Bets

Our model's biggest edge in today's White Sox vs. Reds matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

White Sox vs. Reds Game-Day Updates and Essential Details

Thursday's MLB action between the Reds and White Sox at Great American Ball Park is scheduled to begin at 12:40PM ET.

• Who: Chicago White Sox vs. Cincinnati Reds
• Date: Thursday, May 15, 2025
• Time: 12:40PM ET/9:40AM PT
• Venue: Great American Ball Park

Dimers.com's full preview of Thursday's White Sox vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any CHI White Sox vs. Cincinnati picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Reds, with a 65% win probability, will likely beat the White Sox on Thursday.

AI and automation have enhanced this article to quickly deliver accurate White Sox vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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