Cubs vs. Nationals Prediction: Cubs Predicted to Win Tuesday's MLB Matchup [6/3/2025]

The Washington Nationals will square off with the Chicago Cubs in MLB action at Nationals Park on Tuesday, beginning at 6:45PM ET.

Trevor Williams (3-5, 5.69 ERA) will get the ball for the Nationals, pitting him against Cade Horton (2-0, 3.98 ERA) for the Cubs.

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cubs as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's CHI Cubs-Washington game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Cubs with a win probability of 55%, compared to 45% for the Nationals."

For further insights into Tuesday's matchup, including best bets and picks, visit our interactive Cubs vs. Nationals predictions page.

Nationals vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the result of Tuesday's MLB game between the Cubs and Nationals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Cubs a 55% chance of beating the Nationals.

According to our model, the Nationals (+1.5) have a 57% chance of covering the run line, while the 9.5-run over/under has a 52% chance of staying under.

Cubs vs. Nationals Odds [6/3/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Cubs	Nationals
Run Line	-1.5 (+115)	+1.5 (-135)
Moneyline	-142	+120
Total	o9.5 (-105)	u9.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Cubs vs. Nationals Picks and Best Bets

Our model's biggest edge in today's Cubs vs. Nationals matchup is on the moneyline.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Cubs vs. Nationals Game-Day Updates and Essential Details

Tuesday's MLB action between the Nationals and Cubs at Nationals Park is scheduled to start at 6:45PM ET.

• Who: Chicago Cubs vs. Washington Nationals
• Date: Tuesday, June 3, 2025
• Time: 6:45PM ET/3:45PM PT
• Venue: Nationals Park

Dimers.com's full preview of Tuesday's Cubs vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any CHI Cubs vs. Washington picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Cubs, with a 55% win probability, will likely beat the Nationals on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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