Cubs vs. Blue Jays Prediction: Toronto Predicted to Win Wednesday's MLB Matchup [8/13/2025]

The Toronto Blue Jays and Chicago Cubs will lock horns in MLB action at Rogers Centre on Wednesday, starting at 7:07PM ET.

Kevin Gausman (8-8, 3.85 ERA) will start for the Blue Jays, up against Cade Horton (6-3, 3.18 ERA) for the Cubs.

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Blue Jays as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Cubs-Blue Jays game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Blue Jays' chance of winning at 55%, with the Cubs at 45%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Cubs vs. Blue Jays predictions page.

Blue Jays vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Wednesday's MLB game between the Cubs and Blue Jays 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Blue Jays a 55% chance of defeating the Cubs.

According to our model, the Cubs (+1.5) have a 63% chance of covering the run line, while the 8.5-run over/under has a 52% chance of going over.

Cubs vs. Blue Jays Odds [8/13/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Cubs	Blue Jays
Run Line	+1.5 (-190)	-1.5 (+155)
Moneyline	+115	-134
Total	o8.5 (-108)	u8.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Cubs vs. Blue Jays Picks and Best Bets

Our model's biggest edge in today's Cubs vs. Blue Jays matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Cubs vs. Blue Jays Game-Day Updates and Essential Details

Wednesday's MLB game between the Blue Jays and Cubs at Rogers Centre is scheduled to commence at 7:07PM ET.

• Who: Chicago Cubs vs. Toronto Blue Jays
• Date: Wednesday, August 13, 2025
• Time: 7:07PM ET/4:07PM PT
• Venue: Rogers Centre

Dimers.com's full preview of Wednesday's Cubs vs. Blue Jays matchup includes our prediction, picks and the latest betting odds.

Before making any Cubs vs. Blue Jays picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Blue Jays, with a 55% win probability, will likely beat the Cubs on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Blue Jays insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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