Cubs vs. Cardinals Prediction: Close Contest Projected After New Data Released for Tuesday's MLB Matchup [6/24/2025]

The St. Louis Cardinals and Chicago Cubs will lock horns in MLB action at Busch Stadium on Tuesday, starting at 7:45PM ET.

Michael McGreevy (1-1, 2.70 ERA) will get the ball for the Cardinals, while the Cubs will counter with Jameson Taillon (7-4, 3.84 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts an equal chance for both the Cardinals and Cubs to win today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Cubs-Cardinals game," said Dimers' Chief Content Officer, Nick Slade.

"Based on the latest updates and extensive data, we predict a 50-50 chance for both the Cardinals and Cubs, making it a highly competitive matchup."

For expanded analysis of Tuesday's matchup, including best bets and picks, visit our interactive Cubs vs. Cardinals predictions page.

Cardinals vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the result of Tuesday's MLB game between the Cubs and Cardinals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model can't split the two teams, giving both the Cubs and Cardinals a 50% chance of winning the game.

According to our model, the Cardinals (+1.5) have a 63% chance of covering the run line, while the over/under total of 9 runs has a 52% chance of staying under.

Cubs vs. Cardinals Odds [6/24/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Cubs	Cardinals
Run Line	-1.5 (+146)	+1.5 (-175)
Moneyline	-115	-102
Total	o9 (+103)	u9 (-125)

All odds are correct at the time of publication and are subject to change.

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Cubs vs. Cardinals Picks and Best Bets

Our model's strongest edge in today's Cubs vs. Cardinals matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Cubs vs. Cardinals Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Cardinals and Cubs at Busch Stadium is scheduled to begin at 7:45PM ET.

• Who: Chicago Cubs vs. St. Louis Cardinals
• Date: Tuesday, June 24, 2025
• Time: 7:45PM ET/4:45PM PT
• Venue: Busch Stadium

Dimers.com's full preview of Tuesday's Cubs vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Cubs vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Key MLB Betting Guides and Insights

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Conclusion

We predict a close game between the Cubs and Cardinals on Tuesday, with each team having a 50% chance of winning.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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