Cubs vs. Cardinals Prediction: Cubs Predicted to Win Sunday's MLB Matchup [8/10/2025]

The St. Louis Cardinals will face the Chicago Cubs, in what is expected to be a tight MLB game, at Busch Stadium on Sunday, starting at 7:10PM ET.

Sonny Gray (10-5, 4.21 ERA) will be on the bump for the Cardinals, while the Cubs will counter with Shota Imanaga (8-4, 3.12 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cubs as the most likely winner of today's game. "Using the most recent data, our experts ran 10,000 simulations of Sunday's Cubs-Cardinals game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Cubs with a win probability of 53%, while the Cardinals have 47%."

For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive Cubs vs. Cardinals predictions page.

Cardinals vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB matchup between the Cubs and Cardinals 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Cubs a 53% chance of defeating the Cardinals.

According to our model, the Cardinals (+1.5) have a 62% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of going over.

Cubs vs. Cardinals Odds [8/10/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Cubs	Cardinals
Run Line	-1.5 (+131)	+1.5 (-155)
Moneyline	-126	+115
Total	o7.5 (-105)	u7.5 (-114)

All odds are correct at the time of publication and are subject to change.

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Cubs vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Cubs vs. Cardinals matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Cubs vs. Cardinals Game-Day Updates and Essential Details

Sunday's MLB game between the Cardinals and Cubs at Busch Stadium is scheduled to start at 7:10PM ET.

• Who: Chicago Cubs vs. St. Louis Cardinals
• Date: Sunday, August 10, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Busch Stadium

Dimers.com's comprehensive preview of Sunday's Cubs vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Cubs vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cubs, with a 53% win probability, will likely beat the Cardinals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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