Cubs vs. Cardinals Prediction: Cubs Predicted to Win Saturday's MLB Matchup [8/9/2025]

The St. Louis Cardinals will take on the Chicago Cubs, in what is expected to be a close MLB game, at Busch Stadium on Saturday, beginning at 7:15PM ET.

Andre Pallante (6-8, 4.57 ERA) will start on the mound for the Cardinals, up against Colin Rea (8-5, 4.23 ERA) for the Cubs.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Cubs as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Cubs vs. Cardinals predictions page.

Cardinals vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the result of Saturday's MLB game between the Cubs and Cardinals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Cubs a 52% chance of defeating the Cardinals.

According to our model, the Cardinals (+1.5) have a 61% chance of covering the run line, while the over/under total of 9 runs has a 52% chance of staying under.

Cubs vs. Cardinals Odds [8/9/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Cubs	Cardinals
Run Line	-1.5 (+135)	+1.5 (-156)
Moneyline	-122	+105
Total	o9 (-102)	u9 (-116)

All odds are correct at the time of publication and are subject to change.

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Cubs vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Cubs vs. Cardinals matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Cubs vs. Cardinals Game-Day Updates and Essential Details

Saturday's MLB game between the Cardinals and Cubs at Busch Stadium is scheduled to start at 7:15PM ET.

• Who: Chicago Cubs vs. St. Louis Cardinals
• Date: Saturday, August 9, 2025
• Time: 7:15PM ET/4:15PM PT
• Venue: Busch Stadium

Dimers.com's full preview of Saturday's Cubs vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Cubs vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cubs, with a 52% win probability, will likely beat the Cardinals on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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