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Cubs vs. Brewers Prediction: Cubs Predicted to Win Monday's MLB Matchup [7/28/2025]

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Written by Dave Garofolo

Our expert prediction for Monday's Chicago Cubs vs Milwaukee Brewers matchup.

Chicago Cubs-Milwaukee Brewers Predictions and Game Preview.
American Family Field sets the stage for the MLB matchup between the Chicago Cubs and Milwaukee Brewers this Monday.

The Milwaukee Brewers and Chicago Cubs will lock horns in MLB action at American Family Field on Monday, starting at 7:40PM ET.

The Brewers will start Jacob Misiorowski (4-1, 2.46 ERA), while the Cubs will counter with Matthew Boyd (11-3, 2.20 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Cubs as the most likely winner of today's game.

For further insights into Monday's matchup, including best bets and picks, visit our interactive Cubs vs. Brewers predictions page.

Brewers vs. Cubs Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Monday's MLB matchup between the Cubs and Brewers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Cubs a 51% chance of beating the Brewers.

According to our model, the Brewers (+1.5) have a 62% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of going over.

 

Cubs vs. Brewers Odds [7/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Cubs Brewers
Run Line -1.5 (+154) +1.5 (-170)
Moneyline -115 -102
Total o7.5 (-105) u7.5 (-112)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Cubs vs. Brewers Picks and Best Bets

Our model's biggest edge in today's Cubs vs. Brewers matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Cubs vs. Brewers Game-Day Updates and Essential Details

Monday's MLB action between the Brewers and Cubs at American Family Field is scheduled to commence at 7:40PM ET.

Dimers.com's full preview of Monday's Cubs vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Cubs vs. Brewers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cubs, with a 51% win probability, will likely beat the Brewers on Monday.

AI and automation have enhanced this article to quickly deliver accurate Cubs vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on MLB

Stay informed with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest projections for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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