Charleston Southern vs. Coastal Carolina prediction: Why Coastal Carolina is favored to win in college football Week 2, 2025

Coastal Carolina will face Charleston Southern in Week 2 college football action at Brooks Stadium on Saturday, beginning at 7:30PM ET.

Based on updated simulations, Dimers' proven college football model predicts Coastal Carolina as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Charleston Southern vs. Coastal Carolina predictions page.

Charleston Southern vs. Coastal Carolina prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the result of Charleston Southern vs. Coastal Carolina 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Coastal Carolina a 98% chance of beating Charleston Southern. Our predicted final score has Coastal Carolina winning 38-10.

According to our model, the bookmakers have got it right, and Charleston Southern and Coastal Carolina each have a 50% chance of covering the spread, while the 46.5-point over/under has a 57% chance of going over.

Charleston Southern vs. Coastal Carolina odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Charleston Southern	Coastal Carolina
Spread	+28.5 (-110)	-28.5 (-105)
Moneyline	+3500	-10000
Total	o46.5 (-120)	u46.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Charleston Southern vs. Coastal Carolina picks and best bets

Our model's strongest edge in today's Charleston Southern vs. Coastal Carolina matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Charleston Southern vs. Coastal Carolina game-day updates and essential details

Saturday's college football action between Coastal Carolina and Charleston Southern at Brooks Stadium is scheduled to begin at 7:30PM ET.

• Who: Charleston Southern vs. Coastal Carolina
• Date: Saturday, September 6, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Brooks Stadium

Dimers.com's full preview of Saturday's Charleston Southern vs. Coastal Carolina matchup includes our prediction, picks and the latest betting odds.

Before making any Charleston Southern vs. Coastal Carolina picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Coastal Carolina, with a 98% win probability, will likely beat Charleston Southern on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Charleston Southern vs. Coastal Carolina insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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