Central Michigan vs. Pittsburgh prediction: Why Pittsburgh is favored to win in college football Week 2, 2025

Pittsburgh and Central Michigan will meet in Week 2 college football action at Acrisure Stadium on Saturday, commencing at 12:00PM ET.

Based on updated simulations, Dimers' advanced college football model predicts Pittsburgh as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Central Michigan vs. Pittsburgh predictions page.

Central Michigan vs. Pittsburgh prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the result of Central Michigan vs. Pittsburgh 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Pittsburgh a 93% chance of defeating Central Michigan. Our predicted final score has Pittsburgh winning 35-14.

According to our model, Central Michigan (+23.5) has a 53% chance of covering the spread, while the over/under total of 48.5 points has a 52% chance of staying under.

Central Michigan vs. Pittsburgh odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Central Michigan	Pittsburgh
Spread	+23.5 (-110)	-23.5 (-120)
Moneyline	+1200	-2500
Total	o48.5 (-110)	u48.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Central Michigan vs. Pittsburgh picks and best bets

Our model's strongest edge in today's Central Michigan vs. Pittsburgh matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Central Michigan vs. Pittsburgh game-day updates and essential details

Saturday's college football action between Pittsburgh and Central Michigan at Acrisure Stadium is scheduled to begin at 12:00PM ET.

• Who: Central Michigan vs. Pittsburgh
• Date: Saturday, September 6, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: Acrisure Stadium

Dimers.com's full preview of Saturday's Central Michigan vs. Pittsburgh matchup includes our prediction, picks and the latest betting odds.

Before making any Central Michigan vs. Pittsburgh picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Pittsburgh, with a 93% win probability, will likely beat Central Michigan on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Central Michigan vs. Pittsburgh insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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