Carolina Panthers vs. New England Patriots updated prediction featuring Chuba Hubbard, Rhamondre Stevenson [Week 4, 2025]

Dimers' latest NFL predictions are live for New England Patriots and Carolina Panthers in Week 4, with our model giving the Patriots a 69% of winning against the Panthers on Sunday.

This update builds on our early Patriots-Panthers predictions, adding fresh win probabilities, score projections, and TD predictions for Chuba Hubbard, Rhamondre Stevenson, and more.

For the most accurate simulation-based insights—including spread and total picks, touchdown probabilities, and the full list of player props—head to our Panthers vs. Patriots page.

What's changed? Carolina vs. New England updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Panthers vs. Patriots matchup stacks up. Here are the updated forecasted:

• Straight Up Win Probabilities: Panthers 31%, Patriots 69%
• Predicted Final Score: Panthers 19-24 Patriots
• Spread: Panthers (+5.5) 50%, Patriots (-5.5) 50%
• Total Points (43): Over 57%, Under 43%

As of September 25, 2025, these Panthers-Patriots numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New projections highlight the top candidates to find the end zone in Panthers-Patriots on Sunday:

Carolina Panthers

• Chuba Hubbard: 43.4% probability
• Tetairoa McMillan: 34.7% probability
• Hunter Renfrow: 18.5% probability

New England Patriots

• Rhamondre Stevenson: 34.1% probability
• TreVeyon Henderson: 32.0% probability
• Hunter Henry: 28.7% probability

Panthers vs. Patriots latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Panthers +5.5 (-110), Patriots -5.5 (-110)
• Moneyline: Panthers +205, Patriots -238
• Total: Over/Under 43 (-110/-110)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Panthers vs. Patriots Week 4 details

The NFL Week 4 game between the Patriots and Panthers at Gillette Stadium is scheduled for September 28, 2025.

• Who: Carolina Panthers vs. New England Patriots
• Date: Sunday, September 28, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Gillette Stadium

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Conclusion

We predict the Patriots, with a 69% win probability, will likely beat the Panthers in Week 4 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Panthers vs. Patriots game, with human oversight maintaining high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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