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Parlay these Cardinals vs. Seahawks player props at +500 odds for Thursday Night Football betting

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Written by Dave Garofolo
Reviewed by Nick Slade

It's Week 4 in the NFL and to kick things off, we've built a +500 same game parlay at DraftKings for Cardinals vs. Seahawks on Thursday Night Football.

NFL Parlay bet for Thursday Night Football featuring the Cardinals and Seahawks.
Kyler Murray is one of the league's most consistent rushing QBs - can he do it on TNF?

It's Week 4 in the NFL and we're kicking things off with another Primetime Parlay built with the Dimers model for tonight's Arizona Cardinals vs. Seattle Seahawks Thursday Night Football matchup on September 25, 2025.

This is our biggest NFL season yet on Dimers, with the launch of our brand-new NFL Player Projections Hub, complete with boxscores and fantasy projections, our improved NFL models and the rollout of our new Dimers Sports Betting Podcast.

To kick off Week 4, we're using our model's Thursday Night Football predictions to build a +500 SGP over on DraftKings Sportsbookwhere new users can claim a $200 bonus and a $200 NFL Sunday Ticket discount, expiring after this weekend.


+500 Cardinals-Seahawks NFL Same Game Parlay Picks

After simulating tonight's game over 10,000 times, our model has identified the following projections and probabilities for the picks that make up our three-leg same game parlay in Cardinals vs. Seahawks on Thursday Night Football, September 25.

PlayerPropProjectionsOdds
Kyler Murray (Cardinals)25+ Rushing Yards31.3 Rushing Yards-155
Tory Horton (Seahawks)25+ Receiving Yards30.6 Receiving Yards-116
Ken Walker III (Seahawks)Anytime TD Scorer45.8% Probability+105

MORE: Cardinals vs. Seahawks TNF Full Game Betting Preview

Leg 1: Kyler Murray 25+ Rushing Yards

First up, we're starting with a QB prop but it's not in the passing game. 

With the run game taking a hit in the backfield after James Conner's season-ending injury, Kyler Murray should be as ready to run as he has been all season.

We're looking at Kyler Murray to tally up 25+ rushing yards as the Dimers model has him projected for 31.3 rushing yards.

Murray has hit this in all three games so far with 32+ yards in each and at least 6 carries in those games, which have all been true carries, only 1 end of game kneel down in that tally.

The Seahawks haven’t faced a rushing QB yet, so not much to compare in their previous games, but they have one of the league’s better pass rush win rates so Murray will likely have to scramble a few times in this one.

Leg 2: Tory Horton 25+ Receiving Yards

Our second leg is on Seahawks rookie WR Tory Holton to rack up his own set of 25+ yards through the air.

As we discussed on the Dimers Sports Betting Podcast, Tory Horton is in a prime position to secure the WR2 role in this Seahawks offense.

Cooper Kupp, brought in this offseason, has 11 catches and no touchdowns through three games. Horton has managed two touchdowns on 8 targets in Week 2+3 after a target-less Week 1, and has 32 receiving yards in consecutive games.

Darnold is looking for him and hitting him in key situations, boding well for his future opportunities against a Cardinals defense that's allowed multiple opposing receivers to find success in the passing game.

The Dimer model projects Horton for 30.6 receiving yards on Thursday night and if he takes over this role, we may not seem him at this number with bettable odds anytime soon.

MORE: The Dimers Sports Betting Podcast - Episode 6

Leg 3: Ken Walker III Anytime TD Scorer

We'll close with a TD prop and in this game, it's our most likely TD scorer of them all, Ken Walker III at a 45.7% probability.

K9 has three TDs in his past two games, and while he was horribly inefficient last game vs. the Saints, he scored twice with backfield mate Zach Charbonnet out.

Charbonnet looks to be back but did not look good in his last game and it’s a quick turnaround so he may not be 100% coming off a foot injury.

We should expect the timeshare to resume if Charbonnet is good to go, but Walker gets the benefit of targets out of the backfield, which Charbonnet does not, giving him more paths to score, particularly against a Cardinals team that's allowed a pair of rushing TDs through two games so far.

RELATED: Cardinals vs. Seahawks: The 5 Questions That Could Decide Thursday Night Football

 

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To give you the most accurate and helpful information, this article has been reviewed and edited by Nick Slade through our fact-checking process.
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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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