Cardinals vs. Lions Predictions and Odds - Dec 19, 2021

NFL Week 15 action continues on Sunday at 1:00 PM EST as the favored Arizona Cardinals square off with the Detroit Lions at Ford Field.

Dimers' free betting picks for Cardinals vs. Lions, plus game predictions, best odds and player props, are featured in this article.

Who will win Cardinals vs. Lions?

Using state-of-the-art computer power and data, Dimers.com has simulated Sunday's Cardinals-Lions NFL game 10,000 times.

Dimers' leading predictive analytics model, DimersBOT, gives the Cardinals an 86% chance of getting the W against the Lions.

MORE: Free Betting Analysis for Cardinals vs. Lions

Point Spread, Moneyline and Over/Under

The Lions are +13 underdogs against the Cardinals, with -110 at Caesars Sportsbook the best odds available.

For the favored Cardinals (-13) to cover the spread, FanDuel Sportsbook has the best odds on offer at -108.

Caesars Sportsbook has the best moneyline odds for the Lions at +550, which means you can bet $100 to profit $550, earning a total payout of $650, if they win.

Meanwhile, FanDuel Sportsbook has the best moneyline odds for the Cardinals at -720, where you can risk $720 to win $100, for a total payout of $820, if they come out on top.

The Over/Under sits at 48.5 with FanDuel Sportsbook, which has the best odds for the Over at -108, as well as the best odds for the Under at -112.

As always, make sure you check all the legal sportbooks available in your state for the best NFL odds and lines.

According to DimersBOT, the Lions (+13) are a 53% chance of covering the spread, while the Over/Under total of 48.5 points is a 57% chance of going Under.

MORE: Predictions for Every NFL Week 15 Game

Best Bets for Cardinals vs. Lions

• Spread: Lions +13 at -110 with Caesars Sportsbook (53% probability)
• Moneyline: Lions Win at +550 with Caesars Sportsbook
• Over/Under: Under 48.5 at -112 with FanDuel Sportsbook (57% probability) 🔥

Any time you see a 🔥, that means it's one of Dimers' best bets today across any sport.

While the Cardinals are more likely to win the game, according to DimersBOT, betting on the Lions moneyline is the best option because of the edge found when comparing our data-led probabilities to the betting odds.

Taking advantage of the edges seen here at Dimers is crucial to achieving long-term profitability.

Cardinals vs. Lions Score Prediction

Dimers.com's predicted final score for Arizona vs. Detroit at Ford Field this Sunday has the Cardinals prevailing 29-17.

Use our interactive widget below to see the current Spread, Over/Under and Moneyline probabilities and odds for the game, and click or tap on See Matchup for more.

Dimers has full coverage of this week's Cardinals-Lions matchup, including pre-game predictions, free picks, and live win probabilities.

Cardinals vs. Lions Player Props

Who will score the first touchdown in Cardinals vs. Lions? The data is in.

Listed below are the most likely first touchdown and most likely anytime touchdown scorers for both the Cardinals and Lions, as well as projected player stats.

And you know what, we provide this information to you for FREE to help you choose the best prop picks for Sunday's game.

According to DimersBOT, Arizona's James Conner is most likely to score the first TD in Cardinals vs. Lions.

DimersBOT gives Conner a 13.9% chance of scoring the first TD at Ford Field, while the Cardinals RB is a 53.6% chance of reaching the end zone at any point during the game.

First Touchdown Scorer Probabilities

Arizona Cardinals

• James Conner: 13.9% probability
• Kyler Murray: 8.5% probability
• Chase Edmonds: 8.5% probability
• Christian Kirk: 7.5% probability
• A.J. Green: 7.1% probability

Detroit Lions

• Amon-Ra St. Brown: 7.8% probability
• Josh Reynolds: 5.5% probability
• Jermar Jefferson: 4.3% probability
• Shane Zylstra: 3.7% probability
• Craig Reynolds: 3.5% probability

Anytime Touchdown Scorer Probabilities

Arizona Cardinals

• James Conner: 53.6% probability
• Chase Edmonds: 38.5% probability
• Kyler Murray: 38.0% probability
• Christian Kirk: 33.8% probability
• A.J. Green: 32.6% probability

Detroit Lions

• Amon-Ra St. Brown: 35.2% probability
• Josh Reynolds: 27.8% probability
• Jermar Jefferson: 22.3% probability
• Craig Reynolds: 20.0% probability
• Shane Zylstra: 19.9% probability

Projected Box Score

Of the starting quarterbacks, the Cardinals' Kyler Murray is projected for 253 passing yards and 2.0 passing touchdowns, while the Lions' Jared Goff is expected to throw for 231 yards and 1.2 TDs.

Cardinals Starting QB

• Kyler Murray: 253 Passing Yards, 2.0 Passing TDs

Lions Starting QB

• Jared Goff: 231 Passing Yards, 1.2 Passing TDs

Cardinals Rushing

• James Conner: 52 Rushing Yards, 0.6 TDs
• Chase Edmonds: 40 Rushing Yards, 0.3 TDs
• Kyler Murray: 35 Rushing Yards, 0.5 TDs

Lions Rushing

• Jermar Jefferson: 21 Rushing Yards, 0.1 TDs
• Craig Reynolds: 16 Rushing Yards, 0.1 TDs
• Godwin Igwebuike: 10 Rushing Yards, 0.1 TDs

Cardinals Receiving

• Christian Kirk: 66 Receiving Yards, 0.4 TDs
• A.J. Green: 52 Receiving Yards, 0.4 TDs
• Zach Ertz: 46 Receiving Yards, 0.3 TDs
• Rondale Moore: 43 Receiving Yards, 0.3 TDs
• Antoine Wesley: 24 Receiving Yards, 0.1 TDs

Lions Receiving

• Amon-Ra St. Brown: 52 Receiving Yards, 0.3 TDs
• Josh Reynolds: 44 Receiving Yards, 0.2 TDs
• Khadarel Hodge: 21 Receiving Yards, 0.1 TDs
• Shane Zylstra: 20 Receiving Yards, 0.1 TDs
• Brock Wright: 18 Receiving Yards, 0.1 TDs

Don't forget, DimersBOT updates often, so keep an eye on this page for any changes to our betting analysis ahead of Cardinals vs. Lions on Sunday December 19, 2021.

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Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a partnership with (such as an online sportsbook), we may earn a referral fee.

Cardinals vs. Lions 2021 Game Info

When do the Lions play the Cardinals?

• Date: Sunday December 19, 2021
• Time: 1:00 PM EST / 10:00 AM PST
• Venue: Ford Field

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Want more NFL analysis like this?

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