Cameron Norrie vs. Francisco Comesana prediction, odds, picks for US Open 2025

Cameron Norrie and Francisco Comesana will meet in the second round of the US Open 2025 on Wednesday.

Based on the latest simulations, Dimers' advanced tennis model predicts Cameron Norrie as the most likely winner of the match.

"We have simulated the outcome of Wednesday's Norrie-Comesana match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Cameron Norrie's chance of winning at 66%, with Francisco Comesana at 34%."

For a closer look at Wednesday's match, including best bets and picks, visit our interactive Norrie vs. Comesana predictions page.

Norrie vs. Comesana prediction: Who will win and advance to the Round of 32?

Using innovative machine learning and data analysis, we have simulated the outcome of Wednesday's Norrie-Comesana men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Norrie a 66% chance of defeating Comesana in the US Open 2025.

Additionally, Norrie has a 63% chance of winning the first set, while the under 38.5 games has a 56% chance of hitting, according to our model.

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Cameron Norrie vs. Francisco Comesana odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Norrie	Comesana
Moneyline	-188	+162
First Set	-164	+130
Total Games	o38.5 (-115)	u38.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Norrie vs. Comesana picks and best bets

Our model's strongest edge in today's Norrie vs. Comesana match is on the first set.

Our expert predictions, aligned with the best odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Norrie vs. Comesana updates and essential details

The US Open 2025 match between Cameron Norrie and Francisco Comesana is scheduled to begin on Wednesday at 1:55PM ET.

• Who: Cameron Norrie vs. Francisco Comesana
• Date: Wednesday, August 27, 2025
• Approx. Time: 1:55PM ET/10:55AM PT
• Tournament: US Open Men's Singles 2025
• Round: Second round

All dates and times mentioned in this article are United States Eastern Time unless otherwise stated.

Dimers.com's in-depth preview of Wednesday's Norrie vs. Comesana match includes our prediction, picks and the latest betting odds.

Before making any Cameron Norrie vs. Francisco Comesana picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Cameron Norrie, with a 66% win probability, will likely beat Francisco Comesana at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Norrie vs. Comesana insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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