California vs. San Diego State prediction: California favored to win in college football Week 4, 2025

San Diego State will take on the favored California in Week 4 college football action at Snapdragon Stadium on Saturday, with kickoff at 10:30PM ET.

Based on the latest simulation results, Dimers' advanced college football model predicts California as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive California vs. San Diego State predictions page.

California vs. San Diego State prediction: Who will win, cover the spread?

Using trusted machine learning and data, we have simulated the result of California vs. San Diego State 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives California an 85% chance of defeating San Diego State. Our predicted final score has California winning 30-16.

According to our model, San Diego State (+15.5) has a 54% chance of covering the spread, while the 46.5-point over/under has a 52% chance of going over.

California vs. San Diego State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	California	San Diego State
Spread	-15.5 (-115)	+15.5 (-115)
Moneyline	-550	+470
Total	o46.5 (-110)	u46.5 (-110)

All odds are correct at the time of publication and are subject to change.

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California vs. San Diego State picks and best bets

Our model's strongest edge in today's California vs. San Diego State matchup is on the total.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

California vs. San Diego State game-day updates and essential details

Saturday's college football matchup between San Diego State and California at Snapdragon Stadium is scheduled to begin at 10:30PM ET.

• Who: California vs. San Diego State
• Date: Saturday, September 20, 2025
• Time: 10:30PM ET/7:30PM PT
• Venue: Snapdragon Stadium

Dimers' comprehensive preview of Saturday's California vs. San Diego State matchup includes our prediction, picks and the latest betting odds.

Before making any California vs. San Diego State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict California, with an 85% win probability, will likely beat San Diego State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate California vs. San Diego State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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