California vs. Louisville Prediction: Louisville Predicted to Win College Basketball Matchup [3/5/2025]

College basketball action continues on Wednesday at 9:00PM ET as California looks to defy the odds against Louisville in college basketball action at KFC Yum! Center.

Based on updated simulation results, Dimers' proven college basketball model (see Dimers Pro for full access) predicts Louisville as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has simulated the outcome of Wednesday's California-Louisville game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate Louisville's chance of winning at 90%, with California at 10%."

For expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive California vs. Louisville predictions page.

READER EXCLUSIVE: Use code 20BASKETBALL at checkout now to get 20% off your first month of Dimers Pro! Hurry, this offer won't last long.

California vs. Louisville Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data, we have simulated the outcome of Wednesday's NCAA basketball matchup between California and Louisville 10,000 times as part of our college basketball predictions coverage.

Our famous predictive model currently gives Louisville a 90% chance of beating California. Our predicted final score has Louisville winning 83-69.

According to our model, Louisville (-14.5) has a 52% chance of covering the spread, while the over/under total of 154.5 points has a 52% chance of staying under.

California vs. Louisville Odds

We have researched the best College Basketball odds in America for this game, which are listed here:

Bet Type	California	Louisville
Spread	+14.5 (-115)	-14.5 (-102)
Moneyline	+750	-1200
Total	o154.5 (-110)	u154.5 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Our model's biggest edge in today's California vs. Louisville matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

California vs. Louisville Game-Day Updates and Essential Details

Wednesday's college basketball matchup between Louisville and California at KFC Yum! Center is scheduled to start at 9:00PM ET.

• Who: California vs. Louisville
• Date: Wednesday, March 5, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: KFC Yum! Center

Dimers.com's full preview of Wednesday's California vs. Louisville matchup includes our prediction, picks and the latest betting odds.

Before making any California vs. Louisville picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Sports Betting Deals Available for Wednesday

To make the most of Wednesday's big day of sports, headlined by basketball action across the NBA and college hoops, check out details on the latest Bet365 bonus code "DIMERS" that unlocks the choice of two amazing signup promotions.

Plus, find out all the details on the BetMGM bonus code "DIMERS150" which is now available in AZ, CO, DC, MA, MD, MI, NC, NJ, PA, VA, and WV. Don't miss out!

Conclusion

We predict Louisville, with a 90% win probability, will likely beat California on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate California vs. Louisville insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on College Basketball

Keep up with the latest college basketball betting news, college basketball best bets and CBB parlay picks throughout the season. Plus, our March Madness odds offer the most up-to-date predictions for every March Madness contender.