Butler vs. Northern Iowa prediction: Northern Iowa favored to win in college football Week 1, 2025

Northern Iowa will square off with Butler in college football action at UNI-Dome on Saturday, commencing at 2:00PM ET.

Based on updated simulations, Dimers' proven college football model projects Northern Iowa as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Butler vs. Northern Iowa predictions page.

Butler vs. Northern Iowa prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the outcome of Butler vs. Northern Iowa 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Northern Iowa an 84% chance of defeating Butler. Our predicted final score has Northern Iowa winning 34-18.

According to our model, the bookmakers have got it right, and Butler and Northern Iowa each have a 50% chance of covering the spread, while the 52.5-point over/under has a 52% chance of going over.

Butler vs. Northern Iowa odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type	Butler	Northern Iowa
Spread	+15.5 (-110)	-15.5 (-105)
Moneyline	+525	-690
Total	o52.5 (-110)	u52.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Butler vs. Northern Iowa picks and best bets

Our model's biggest edge in today's Butler vs. Northern Iowa matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Butler vs. Northern Iowa game-day updates and essential details

Saturday's college football action between Northern Iowa and Butler at UNI-Dome is scheduled to commence at 2:00PM ET.

• Who: Butler vs. Northern Iowa
• Date: Saturday, August 30, 2025
• Time: 2:00PM ET/11:00AM PT
• Venue: UNI-Dome

Dimers.com's comprehensive preview of Saturday's Butler vs. Northern Iowa matchup includes our prediction, picks and the latest betting odds.

Before making any Butler vs. Northern Iowa picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Northern Iowa, with an 84% win probability, will likely beat Butler on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Butler vs. Northern Iowa insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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