Premier League- More Betting
Burnley vs. Southampton Prediction and Odds - Apr 21, 2022

Burnley squares off with Southampton in Premier League action at Turf Moor on Thursday, beginning at 2:45PM ET.
Dimers' top betting picks for Burnley vs. Southampton, plus match predictions and best odds, are detailed in this article.
Who will win Burnley vs. Southampton?
Based on trusted machine learning and data, Dimers.com has simulated Thursday's Burnley-Southampton Premier League match 10,000 times.
Dimers' independent predictive analytics model, DimersBOT, currently gives Burnley a 33.2% chance of winning, Southampton a 40.8% chance of winning, and the draw a 26.0% chance of happening.
More: Burnley vs. Southampton Simulated 10,000 Times
Burnley vs. Southampton Current Odds
- Moneyline: Burnley +165, Southampton +180, Draw +240
- Total Goals: Over/Under 2.5 (+100/-115)
Moneyline and Over/Under
BetMGM currently has the best moneyline odds for Burnley at +165. That means you can bet $100 to profit $165, earning a total payout of $265, if it wins.
Meanwhile, DraftKings Sportsbook currently has the best moneyline odds for Southampton at +180, where you can put down $100 to profit $180, earning a total payout of $280, if it wins.
Lastly, BetMGM currently has the best odds for the draw at +240, which means you can bet $100 to win $240, for a total payout of $340, if it hits.
The Over/Under for total goals scored sits at 2.5 with Caesars Sportsbook, which currently has the best odds for the Over at +100, while DraftKings Sportsbook currently has the best odds for the Under at -115.
As always, make sure you check all the legal sportbooks that are available in your state for the best Premier League odds and lines.
According to DimersBOT, the 2.5-goal Over/Under is a 51% chance of going Under.
More: Live Scores for All Major Sports
Best Bets for Burnley vs. Southampton
- Moneyline: Southampton @ +180 via DraftKings Sportsbook (5.0% edge) 🔥
- Total Goals: Over 2.5 @ +100 via Caesars Sportsbook
Every time you see a 🔥, you know it's one of our best bets today across all sports.
Dimers' best bets are based on detailed simulations and betting intelligence to help you make smarter investments with the legal sportsbooks in your state.
Despite the Under being more likely to hit on this occasion, Over 2.5 is our best bet on account of the better odds (+100) that are available from Caesars Sportsbook.
Burnley vs. Southampton Probabilities
Use our interactive widget below to view up-to-date Moneyline, Correct Score and Over/Under probabilities and odds for the match, and click or tap on See Matchup for more.
Dimers has full betting coverage of Thursday's Burnley-Southampton match, including pregame predictions, computer picks, and live win probabilities.
Remember, DimersBOT updates often, so refresh this page for the latest betting insights ahead of Burnley vs. Southampton on Thursday April 21, 2022.
Risk-Free Bet for Burnley vs. Southampton
Are you looking to bet on Burnley vs. Southampton? Join FanDuel Sportsbook now and get a risk-free first bet up to $1,000, which you can use on Thursday's match.
Simply click or tap on this exclusive FanDuel Sportsbook link and create an account – it's easy and takes less than 2 minutes.
Then, make your first deposit and place a bet up to $1,000 on Burnley vs. Southampton. If your bet doesn't win, FanDuel Sportsbook will refund it in site credit!
This promo is available to all new FanDuel Sportsbook users. How good is that!
Note: when you click or tap on a link on Dimers that leads to a third-party website that we have a commercial arrangement with (such as a sportsbook), we may earn a referral fee.
Burnley vs. Southampton 2022 Match Info
What time does Burnley vs. Southampton start in USA?
- Date: Thursday April 21, 2022
- Time: 2:45PM ET / 11:45AM PT
- Venue: Turf Moor
Looking to join an online sportsbook and start betting on ⚽️ in the United States? Check out the top sportsbook offers in your state.
Want more Premier League analysis like this?
So, you liked our Burnley vs. Southampton betting predictions? Awesome. Did you know our Premier League Betting News page has a comprehensive betting preview for every English Premier League game as soon as the sportsbooks put out their odds?
That's right, our predictive analytics model then compares those odds (aka Vegas odds) against its own probabilities to find value in the markets. This allows us to produce the most reliable Premier League betting previews and beat the public and the sportsbooks to the punch.
It's only a click away, so why not take a look around?