Buffalo Bills vs. Tennessee Titans NFL Betting Picks, Predictions and Props: Monday October 18, 2021

The Bills find themselves entering MNF as the joint Super Bowl favorites with a chance to further solidify their status as contenders against a Titans team that are always capable of springing a surprise.

The NFL season continues on Monday October 18, 2021, and, as always, Dimers.com has simulated Bills vs. Titans 10,000 times to determine where the value lies for football bettors across the United States.

With NFL betting picks, probabilities, odds and predicted scores featured each and every week at Dimers, check out our top plays for this NFL 2021 Week 6 matchup.

This Sunday's NFL best bets and odds are proudly brought to you by BetMGM.

NFL 2021 Week 6 MNF: Bills vs. Titans

💰 Best Bet

For our best bet, we're zoning in the total. Buffalo's defense has accumulated two shutouts already this year while being able to limit the pass offense of their opponents, giving up just 173 yards per game on average which is the best mark in the league. This is simply too high a total for such a strangling defense, even if the Bills have been tremendous on offense. Our data projections says the Under is the play.

BET: Under 53.5 (-110)

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🔥 Best Player Prop

Luckily for the Titans, they have one of the best running weapons in the league in Derrick Henry. With the anticipated stifling of Tannehill, Henry should see a lot of action as Tennessee try to unpick the Bills secondary.

This is a crazy line to take advantage of considering the RB's last four games:

• 130 Rush Yds vs. Jags
• 157 Rush Yds vs. Jets
• 113 Rush Yds vs. Colts
• 182 Rush Yds vs. Seahawks

PICK: Derrick Henry o98.5 Rushing Yds (-113)‍‍

‍MORE: Bills vs. Titans simulator

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Best Monday Night Football Sportsbook Offers

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DraftKings Sportsbook Bet $1, Get $100

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FUTURES: 2022 Super Bowl probabilities

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NFL Schedule Week 6 2021

Thursday October 14, 2021

• Tampa Bay Buccaneers at Philadelphia Eagles, 8:20PM ET (Thursday Night Football)

Sunday October 17, 2021

• Miami Dolphins vs. Jacksonville Jaguars (London, UK), 9:30AM 
• Los Angeles Chargers at Baltimore Ravens, 1PM
• Minnesota Vikings at Carolina Panthers, 1PM
• Green Bay Packers at Chicago Bears, 1PM
• Cincinnati Bengals at Detroit Lions, 1PM
• Houston Texans at Indianapolis Colts, 1PM
• Los Angeles Rams at New York Giants, 1PM
• Kansas City Chiefs at Washington Football Team, 1PM
• Arizona Cardinals at Cleveland Browns, 4:05PM
• Las Vegas Raiders at Denver Broncos, 4:25PM
• Dallas Cowboys at New England Patriots, 4:25PM
• Seattle Seahawks at Pittsburgh Steelers, 8:20PM ET (Sunday Night Football)

Monday October 18, 2021

• Buffalo Bills at Tennessee Titans, 8:15PM ET (Monday Night Football)

Week 6 byes: Jets, Falcons, Saints, 49ers