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Bills vs. Jets prediction: Buffalo favored to win in NFL Week 2, 2025
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Buffalo Bills vs New York Jets predictions for NFL Sunday.
The New York Jets and Buffalo Bills are scheduled to meet in Week 2 of the NFL season at MetLife Stadium on Sunday, with kickoff at 1:00PM ET.
Based on updated simulations, Dimers' proven NFL model projects the Bills as the most likely winner of today's game.
"Using the most recent data, our experts ran 10,000 simulations of Sunday's Bills-Jets game," said Dimers' Chief Content Officer, Nick Slade.
"After accounting for recent updates and other variables, our prediction shows the Bills with a win probability of 66%, while the Jets have 34%."
This gameday Bills vs. Jets betting preview builds on my Bills vs. Jets prediction that was released earlier in the week.
For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Bills vs. Jets predictions page.
Bills vs. Jets Predictions
Since our Bills-Jets predictions earlier in the week, we have simulated the result of Sunday's NFL game between the Bills and Jets 10,000 times as part of our NFL predictions coverage.
Our famous predictive model gives the Bills a 66% chance of beating the Jets in Week 2 of the NFL season. Our predicted final score has the Bills winning 25-21.
According to our model, the Jets (+6) have a 56% chance of covering the spread, while the 47.5-point over/under has an equal 50-50 chance of hitting.
Bills vs. Jets odds
We have researched the best NFL odds in America for this game, which are listed here:
| Bet Type | Bills | Jets |
|---|---|---|
| Spread | -6 (-112) | +6 (-108) |
| Moneyline | -275 | +235 |
| Total | o47.5 (+100) | u47.5 (-110) |
All odds are correct at the time of publication and are subject to change.
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Bills vs. Jets picks and best bets
Our model's biggest edge in today's Bills vs. Jets matchup is on the moneyline.
Our expert predictions, aligned with the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Bills vs. Jets TD scorers
Who will score an anytime touchdown in Bills vs. Jets?
According to our model, Buffalo's James Cook is most likely to score the first touchdown in Bills vs. Jets.
Our projections give Cook a 13.6% chance of scoring the first TD at MetLife Stadium, while the Bills running back is a 54.8% chance of registering an anytime touchdown.
First touchdown scorer predictions
Buffalo Bills
| Player | First TD Probability |
|---|---|
| James Cook (RB) | 13.6% |
| Josh Allen (QB) | 11.2% |
| Keon Coleman (WR) | 5.4% |
New York Jets
| Player | First TD Probability |
|---|---|
| Breece Hall (RB) | 9.6% |
| Justin Fields (QB) | 9.0% |
| Garrett Wilson (WR) | 6.7% |
Anytime touchdown scorer predictions
Buffalo Bills
| Player | Anytime TD Probability |
|---|---|
| James Cook (RB) | 54.8% |
| Josh Allen (QB) | 48.0% |
| Keon Coleman (WR) | 27.2% |
New York Jets
| Player | Anytime TD Probability |
|---|---|
| Breece Hall (RB) | 38.0% |
| Justin Fields (QB) | 36.1% |
| Garrett Wilson (WR) | 28.2% |
Bills vs Jets player props
Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Bills and Jets. For detailed projections, join Dimers Pro.
Already a Dimers Pro member? Head to our Bills-Jets page now to access every player prop projection.
Bills vs. Jets quarterbacks
Of the starting quarterbacks, the Bills' Josh Allen is projected to throw for more yards than the Jets' Justin Fields.
Bills rushing
James Cook, Josh Allen and Ray Davis are projected to be the leading rushers for the Bills.
| Player | Position |
|---|---|
| James Cook | RB |
| Josh Allen | QB |
| Ray Davis | RB |
Jets rushing
Breece Hall, Justin Fields and Braelon Allen are expected to lead the Jets in rushing yards.
| Player | Position |
|---|---|
| Breece Hall | RB |
| Justin Fields | QB |
| Braelon Allen | RB |
Bills receiving
Khalil Shakir, Keon Coleman, Joshua Palmer, Dalton Kincaid and James Cook are projected to top the receiving yards for the Bills.
| Player | Position |
|---|---|
| Khalil Shakir | WR |
| Keon Coleman | WR |
| Joshua Palmer | WR |
| Dalton Kincaid | TE |
| James Cook | RB |
Jets receiving
Garrett Wilson, Tyler Johnson, Mason Taylor, Breece Hall and Allen Lazard are projected to lead the Jets in receiving yards.
| Player | Position |
|---|---|
| Garrett Wilson | WR |
| Tyler Johnson | WR |
| Mason Taylor | TE |
| Breece Hall | RB |
| Allen Lazard | WR |
Bills vs. Jets game-day updates and essential details
The NFL Week 2 game between the Jets and Bills at MetLife Stadium is scheduled to commence at 1:00PM ET.
- Who: Buffalo Bills vs. New York Jets
- Date: Sunday, September 14, 2025
- Time: 1:00PM ET/10:00AM PT
- Venue: MetLife Stadium
Dimers' comprehensive preview of this week's Bills vs. Jets matchup includes our prediction, picks and the latest betting odds.
Before making any Bills vs. Jets picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Bills, with a 66% win probability, will likely beat the Jets in Week 2 of the NFL season.
AI and automation have enhanced this article to quickly deliver accurate Bills vs. Jets insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on NFL
Stay informed with the latest NFL betting news and NFL parlay picks throughout the season. Plus, our Super Bowl odds provide the most up-to-date predictions for the Super Bowl, AFC, NFC and each division.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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