Geelong Cats vs. Brisbane Lions prediction: Cats favored to win Saturday's AFL Round 28 matchup [9/27/2025]

The Geelong Cats will take on the Brisbane Lions in Australian Football League (AFL) action at Melbourne Cricket Ground on Saturday, commencing at 12:30AM ET.

Based on updated simulation results, Dimers' proven AFL model projects the Cats as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Lions vs. Cats predictions page.

Cats vs. Lions prediction: Who will win Round 28 game?

Using innovative machine learning and data, we have simulated the outcome of Saturday's AFL matchup between the Lions and Cats 10,000 times as part of our AFL predictions coverage.

Our independent predictive model currently gives the Cats a 69% chance of beating the Lions.

According to our model, the Lions (+12.5) have a 51% chance of covering the spread, while the over/under total of 176.5 has a 57% chance of staying under.

Brisbane vs. Geelong odds

We have sourced the best AFL odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Cats vs. Lions game-day updates and essential details

Saturday's Australian rules football game between the Cats and Lions at Melbourne Cricket Ground is scheduled to commence at 12:30AM ET.

• Who: Brisbane Lions vs. Geelong Cats
• Date: Saturday, September 27, 2025
• Time: 12:30AM ET/9:30PM PT
• Venue: Melbourne Cricket Ground

The AFL is available to bet on in the US through all major sportsbooks, with fans highlighting the high-octane 360-degree nature of the sport as a top reason to follow it.

Dimers' full preview of Saturday's Lions vs. Cats matchup includes our prediction, picks and the latest betting odds.

Before making any Brisbane vs. Geelong picks, be sure to check out the latest AFL predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cats, with a 69% win probability, will likely beat the Lions on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Lions vs. Cats insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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