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Red Sox vs. Phillies Prediction: Philadelphia Predicted to Win Monday's MLB Matchup [7/21/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Our expert prediction for Monday's Boston Red Sox vs Philadelphia Phillies matchup.
The Philadelphia Phillies will take on the Boston Red Sox in MLB action at Citizens Bank Park on Monday, starting at 6:45PM ET.
The Phillies will have Zack Wheeler (9-3, 2.36 ERA) as their starting pitcher, while the Red Sox have opted for Walker Buehler (6-6, 6.12 ERA).
Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Phillies as the most likely winner of today's game.
For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Red Sox vs. Phillies predictions page.
Phillies vs. Red Sox Prediction: Who Will Win, Cover the Run Line?
Using powerful machine learning and data analysis, we have simulated the outcome of Monday's MLB game between the Red Sox and Phillies 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Phillies a 65% chance of defeating the Red Sox.
According to our model, the Red Sox (+1.5) have a 52% chance of covering the run line, while the over/under total of 7.5 runs has a 54% chance of going over.
Red Sox vs. Phillies Odds [7/21/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Red Sox | Phillies |
|---|---|---|
| Run Line | +1.5 (+105) | -1.5 (-114) |
| Moneyline | +197 | -235 |
| Total | o7.5 (-120) | u7.5 (-102) |
All odds are correct at the time of publication and are subject to change.
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Red Sox vs. Phillies Picks and Best Bets
Our model's strongest edge in today's Red Sox vs. Phillies matchup is on the over/under.
Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free ⚾️ Picks
Calling Our Shot produces daily MLB betting content, including the free picks featured below.
Red Sox vs. Phillies Game-Day Updates and Essential Details
Monday's MLB action between the Phillies and Red Sox at Citizens Bank Park is scheduled to begin at 6:45PM ET.
- Who: Boston Red Sox vs. Philadelphia Phillies
- Date: Monday, July 21, 2025
- Time: 6:45PM ET/3:45PM PT
- Venue: Citizens Bank Park
Dimers.com's in-depth preview of Monday's Red Sox vs. Phillies matchup includes our prediction, picks and the latest betting odds.
Before making any Red Sox vs. Phillies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Conclusion
We predict the Phillies, with a 65% win probability, will likely beat the Red Sox on Monday.
AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Phillies insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on MLB
Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most up-to-date projections for the World Series, American League, National League and each division.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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