Red Sox vs. Angels Prediction: Angels Predicted to Win Wednesday's MLB Matchup [6/25/2025]

The Los Angeles Angels will face the Boston Red Sox in MLB action at Angel Stadium on Wednesday, starting at 4:07PM ET.

Yusei Kikuchi (2-6, 3.01 ERA) will start for the Angels, pitting him against Richard Fitts (0-3, 4.71 ERA) for the Red Sox.

Based on the latest simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Angels as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Red Sox-Angels game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Angels' chance of winning at 58%, with the Red Sox at 42%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Red Sox vs. Angels predictions page.

Angels vs. Red Sox Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Red Sox and Angels 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Angels a 58% chance of defeating the Red Sox.

According to our model, the Red Sox (+1.5) have a 60% chance of covering the run line, while the 8.5-run over/under has a 52% chance of staying under.

Red Sox vs. Angels Odds [6/25/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Red Sox	Angels
Run Line	+1.5 (-192)	-1.5 (+158)
Moneyline	+110	-130
Total	o8.5 (-118)	u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Red Sox vs. Angels Picks and Best Bets

Our model's biggest edge in today's Red Sox vs. Angels matchup is on the run line.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Red Sox vs. Angels Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Angels and Red Sox at Angel Stadium is scheduled to begin at 4:07PM ET.

• Who: Boston Red Sox vs. Los Angeles Angels
• Date: Wednesday, June 25, 2025
• Time: 4:07PM ET/1:07PM PT
• Venue: Angel Stadium

Dimers.com's full preview of Wednesday's Red Sox vs. Angels matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Angels picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Angels, with a 58% win probability, will likely beat the Red Sox on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Angels insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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