Red Sox vs. Astros Prediction: Houston Predicted to Win Tuesday's MLB Matchup [8/12/2025]

The Houston Astros and Boston redsox are scheduled to meet in MLB action at Daikin Park on Tuesday, starting at 8:10PM ET.

The Astros will have Spencer Arrighetti (1-2, 7.42 ERA) as their starting pitcher, while the Red Sox have opted for Dustin May (6-8, 4.93 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) projects the Astros as the most likely winner of today's game.

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Red Sox vs. Astros predictions page.

Astros vs. Red Sox Prediction: Who Will Win?

Using powerful machine learning and data, we have simulated the outcome of Tuesday's MLB game between the Red Sox and Astros 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Astros a 52% chance of defeating the Red Sox.

According to our model, the 8.5-run over/under also has an equal 50-50 chance of hitting.

Red Sox vs. Astros Odds [8/12/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Red Sox	Astros
Moneyline	-105	-108
Total	o8.5 (-132)	u8.5 (+108)

All odds are correct at the time of publication and are subject to change.

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Red Sox vs. Astros Picks and Best Bets

Our model's strongest edge in today's Red Sox vs. Astros matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Red Sox vs. Astros Game-Day Updates and Essential Details

Tuesday's MLB action between the Astros and Red Sox at Daikin Park is scheduled to begin at 8:10PM ET.

• Who: Boston Red Sox vs. Houston Astros
• Date: Tuesday, August 12, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: Daikin Park

Dimers.com's full preview of Tuesday's Red Sox vs. Astros matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Astros picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Astros, with a 52% win probability, will likely beat the Red Sox on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Astros insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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