Red Sox vs. Tigers Prediction: Detroit Predicted to Win Wednesday's MLB Matchup [5/14/2025]

The Detroit Tigers will square off with the Boston Red Sox in MLB action at Comerica Park on Wednesday, commencing at 6:40PM ET.

Tarik Skubal (4-2, 2.08 ERA) will start on the mound for the Tigers, pitting him against Hunter Dobbins (2-1, 2.78 ERA) for the Red Sox.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Tigers as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Boston-Detroit game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Tigers' chance of winning at 66%, with the Red Sox at 34%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Red Sox vs. Tigers predictions page.

Tigers vs. Red Sox Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB game between the Red Sox and Tigers 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Tigers a 66% chance of beating the Red Sox.

According to our model, the Red Sox (+1.5) have a 54% chance of covering the run line, while the 7-run over/under has a 52% chance of going over.

Red Sox vs. Tigers Odds [5/14/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Red Sox	Tigers
Run Line	+1.5 (-110)	-1.5 (-104)
Moneyline	+205	-235
Total	o7 (-110)	u7 (-110)

All odds are correct at the time of publication and are subject to change.

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Red Sox vs. Tigers Picks and Best Bets

Our model's strongest edge in today's Red Sox vs. Tigers matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Red Sox vs. Tigers Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Tigers and Red Sox at Comerica Park is scheduled to start at 6:40PM ET.

• Who: Boston Red Sox vs. Detroit Tigers
• Date: Wednesday, May 14, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Comerica Park

Dimers.com's full preview of Wednesday's Red Sox vs. Tigers matchup includes our prediction, picks and the latest betting odds.

Before making any Boston vs. Detroit picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Tigers, with a 66% win probability, will likely beat the Red Sox on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Tigers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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