Red Sox vs. Cubs Prediction: Cubs Predicted to Win Friday's MLB Matchup [7/18/2025]

The Chicago Cubs will face the Boston Red Sox in MLB action at Wrigley Field on Friday, starting at 2:20PM ET.

The Cubs will send Colin Rea (7-3, 3.91 ERA) to the mound, while the Red Sox have opted for Lucas Giolito (6-1, 3.36 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Cubs as the most likely winner of today's game.

For further insights into Friday's matchup, including best bets and picks, visit our interactive Red Sox vs. Cubs predictions page.

Cubs vs. Red Sox Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the outcome of Friday's MLB matchup between the Red Sox and Cubs 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Cubs a 55% chance of defeating the Red Sox.

According to our model, the Red Sox (+1.5) have a 64% chance of covering the run line, while the over/under total of 11.5 runs has a 83% chance of staying under.

Red Sox vs. Cubs Odds [7/18/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Red Sox	Cubs
Run Line	+1.5 (-119)	-1.5 (+155)
Moneyline	+148	-135
Total	o11.5 (+101)	u11.5 (-131)

All odds are correct at the time of publication and are subject to change.

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Red Sox vs. Cubs Picks and Best Bets

Our model's strongest edge in today's Red Sox vs. Cubs matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Red Sox vs. Cubs Game-Day Updates and Essential Details

Friday's MLB action between the Cubs and Red Sox at Wrigley Field is scheduled to start at 2:20PM ET.

• Who: Boston Red Sox vs. Chicago Cubs
• Date: Friday, July 18, 2025
• Time: 2:20PM ET/11:20AM PT
• Venue: Wrigley Field

Dimers.com's comprehensive preview of Friday's Red Sox vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Cubs, with a 55% win probability, will likely beat the Red Sox on Friday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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