Red Sox vs. Orioles prediction: Boston favored to win Thursday's MLB matchup [8/28/2025]

MLB action continues on Thursday at 1:05PM ET as the favored Boston Red Sox take on the Baltimore Orioles at Oriole Park at Camden Yards.

Cade Povich (2-7, 5.13 ERA) will be the starting pitcher for the Orioles, while the Red Sox will counter with Garrett Crochet (14-5, 2.38 ERA).

Based on updated simulation results, Dimers' advanced MLB model predicts the Red Sox as the most likely winner of today's game.

For a closer look at Thursday's matchup, including best bets and picks, visit our interactive Red Sox vs. Orioles predictions page.

Orioles vs. Red Sox prediction: Who will win, cover the run line?

Using powerful machine learning and data analysis, we have simulated the outcome of Thursday's MLB game between the Red Sox and Orioles 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Red Sox a 61% chance of defeating the Orioles.

According to our model, the Orioles (+1.5) have a 53% chance of covering the run line, while the 8-run over/under has a 51% chance of going over.

Red Sox vs. Orioles odds [8/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Red Sox	Orioles
Run Line	-1.5 (-122)	+1.5 (+105)
Moneyline	-205	+172
Total	o8 (-114)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Red Sox vs. Orioles picks and best bets

Our model's biggest edge in today's Red Sox vs. Orioles matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Red Sox vs. Orioles game-day updates and essential details

Thursday's MLB action between the Orioles and Red Sox at Oriole Park at Camden Yards is scheduled to commence at 1:05PM ET.

• Who: Boston Red Sox vs. Baltimore Orioles
• Date: Thursday, August 28, 2025
• Time: 1:05PM ET/10:05AM PT
• Venue: Oriole Park at Camden Yards

Dimers.com's comprehensive preview of Thursday's Red Sox vs. Orioles matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Orioles picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Red Sox, with a 61% win probability, will likely beat the Orioles on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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