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Red Sox vs. Orioles prediction: Boston favored to win Monday's MLB matchup [8/25/2025]

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Written by Jason Bevilacqua

Get Boston Red Sox vs Baltimore Orioles predictions for MLB Monday.

Boston Red Sox-Baltimore Orioles Predictions and Game Preview.
Boston Red Sox vs. Baltimore Orioles MLB prediction for Monday, August 25, 2025.

The Baltimore Orioles and Boston redsox will lock horns in MLB action at Oriole Park at Camden Yards on Monday, starting at 6:35PM ET.

The Orioles will have Tomoyuki Sugano (10-5, 3.98 ERA) as their starting pitcher, up against Brennan Bernardino (4-2, 2.94 ERA) for the Red Sox.

Based on the latest simulations, Dimers' advanced MLB model predicts the Red Sox as the most likely winner of today's game.

For expanded analysis of Monday's matchup, including best bets and picks, visit our interactive Red Sox vs. Orioles predictions page.

Orioles vs. Red Sox prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Red Sox and Orioles 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Red Sox a 54% chance of defeating the Orioles.

According to our model, the Orioles (+1.5) have a 59% chance of covering the run line, while the 9.5-run over/under has a 53% chance of staying under.

 

Red Sox vs. Orioles odds [8/25/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Red Sox Orioles
Run Line -1.5 (+135) +1.5 (-160)
Moneyline -118 +100
Total o9.5 (+100) u9.5 (-122)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Red Sox vs. Orioles picks and best bets

Our model's strongest edge in today's Red Sox vs. Orioles matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Red Sox vs. Orioles game-day updates and essential details

Monday's MLB action between the Orioles and Red Sox at Oriole Park at Camden Yards is scheduled to start at 6:35PM ET.

Dimers.com's full preview of Monday's Red Sox vs. Orioles matchup includes our prediction, picks and the latest betting odds.

Before making any Red Sox vs. Orioles picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Red Sox, with a 54% win probability, will likely beat the Orioles on Monday.

AI and automation have enhanced this article to quickly deliver accurate Red Sox vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest probabilities for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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