Boston College vs. Michigan State prediction: Why Michigan State is favored to win in college football Week 2, 2025

Michigan State and Boston College will clash in Week 2 college football action at Spartan Stadium on Saturday, starting at 7:30PM ET.

Based on the latest simulation results, Dimers' advanced college football model predicts Michigan State as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Boston College vs. Michigan State predictions page.

Boston College vs. Michigan State prediction: Who will win, cover the spread?

Using trusted machine learning and statistical analysis, we have simulated the result of Boston College vs. Michigan State 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Michigan State a 65% chance of beating Boston College. Our predicted final score has Michigan State winning 26-21.

According to our model, Michigan State (-3.5) has a 54% chance of covering the spread, while the over/under total of 45.5 points has a 54% chance of staying under.

Boston College vs. Michigan State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Boston College	Michigan State
Spread	+3.5 (-110)	-3.5 (-110)
Moneyline	+164	-170
Total	o45.5 (+100)	u45.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Boston College vs. Michigan State picks and best bets

Our model's strongest edge in today's Boston College vs. Michigan State matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Boston College vs. Michigan State game-day updates and essential details

Saturday's college football matchup between Michigan State and Boston College at Spartan Stadium is scheduled to begin at 7:30PM ET.

• Who: Boston College vs. Michigan State
• Date: Saturday, September 6, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Spartan Stadium

Dimers.com's comprehensive preview of Saturday's Boston College vs. Michigan State matchup includes our prediction, picks and the latest betting odds.

Before making any Boston College vs. Michigan State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Michigan State, with a 65% win probability, will likely beat Boston College on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Boston College vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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