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Celtics vs. Knicks Prediction: New York to Win, Jalen Brunson Projected for Big Game in Game 6 [2025]
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Our expert prediction for Friday's Boston Celtics vs New York Knicks Game 6 matchup.
The New York Knicks and Boston Celtics will meet in the 2025 NBA Playoffs at Madison Square Garden on Friday, with tipoff at 8:00PM ET.
Based on updated simulation results and today’s injury reports, Dimers' proven NBA model (see Dimers Pro for full access) predicts the Knicks as the most likely winner of Game 6.
"Employing the latest data, our experts simulated Friday's Boston-New York game 10,000 times," said Damien Souness from Dimers.
"After computing the latest updates and thousands of other inputs, we predict the Knicks' chance of winning is 62%, while the Celtics' is 38%."
This prediction follows the latest NBA Injury Report, which suggests the Knicks lineup will feature stars like Jalen Brunson, Karl-Anthony Towns and OG Anunoby, while the Celtics will look to Jaylen Brown, Derrick White and Payton Pritchard.
For a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Celtics vs. Knicks predictions page.
Knicks vs. Celtics Prediction: Who Will Win Game 6?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Friday's NBA Playoffs game between the Celtics and Knicks 10,000 times as part of our NBA predictions coverage.
Our leading predictive model currently gives the Knicks a 62% chance of beating the Celtics in Game 6 of the series. Our predicted final score has the Knicks winning 107-104.
According to our model, the Knicks (-3) have a 51% chance of covering the spread, while the over/under total of 210.5 points has a 52% chance of going over.
Celtics vs. Knicks Game 6 Odds
We have researched the best NBA odds in America for this game, which are listed here:
| Bet Type | Celtics | Knicks |
|---|---|---|
| Spread | +3 (-108) | -3 (-108) |
| Moneyline | +130 | -142 |
| Total | o210.5 (-110) | u210.5 (-106) |
All odds are correct at the time of publication and are subject to change.
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Celtics vs. Knicks Picks and Best Bets for Game 6
Our model's strongest edge in today's Celtics vs. Knicks matchup is on the moneyline.
Our expert predictions, aligned with the best odds, reveal the best NBA picks and NBA best bets for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Celtics vs. Knicks Game 6 Player Props
Looking for Boston vs. New York NBA player props? We have crunched the numbers to project how each team's leading players will perform at Madison Square Garden.
Jaylen Brown is expected to lead the Celtics in scoring, while Jalen Brunson is projected to be the top scorer for the Knicks.
Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.
Calling Our Shot's Best Bets Video
Calling Our Shot produces daily NBA betting content, including the best bets featured below.
Celtics vs. Knicks Game 6 Updates and Essential Details
Friday's Game 6 between the Knicks and Celtics in the NBA Playoffs is scheduled to begin at 8:00PM ET.
- Who: Boston Celtics vs. New York Knicks
- Date: Friday, May 16, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Madison Square Garden
- NBA Playoffs Bracket: Updated NBA Playoffs bracket and schedule
The NBA Playoffs is an annual elimination tournament held to determine the league's champion.
Sixteen teams, including the Celtics and Knicks, made the 2025 NBA Playoffs, which spans four rounds: the First Round, Conference Semifinals, Conference Finals, and NBA Finals.
Each round is played as a best-of-seven series, with the first team to four wins advancing to the next round until a champion is crowned. Dimers.com's in-depth preview of Friday's Celtics vs. Knicks matchup includes our prediction, picks and the latest betting odds.
Before making any Boston vs. New York picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.
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Conclusion
We predict the Knicks, with a 62% win probability, will likely beat the Celtics on Friday.
AI and automation have enhanced this article to quickly deliver accurate Celtics vs. Knicks insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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