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Best NFL Betting Picks, Predictions and Parlays: Week 1, Sunday September 12, 2021
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
We are officially in the midst of NFL season! With a huge first Sunday coming up, we go through the games to deliver our best picks of the day.
The 2021 NFL season continues on Sunday September 12, 2021, and, as always, Dimers.com has every Week 1 game to determine where the value lies for football bettors across the United States.
With NFL betting picks, probabilities, odds and predicted scores featured each and every week at Dimers, check out our top plays for Sunday's NFL games.
Today's NFL best bets and odds are proudly brought to you by TwinSpires Sportsbook.
Free NFL Picks For Sunday September 12, 2021
Steelers vs. Bills
BET: Bills -6.5 with TwinSpires (-109)
📈 59% probability
These two teams are going in different directions. The Bills look set to take another step forward this season and compete for the Super Bowl, whilst the Steelers are on a downward trajectory after starting last season 12-0.
Josh Allen and Stefon Diggs form one of the best QB-WR duos in the league and along with other offensive weapons like Devin Singletary, Zack Moss and Cole Beasley, they should be able to overpower Pittsburgh and win this by more than a tuddy - and DimersBOT has them as a 59% chance to cover.
MORE: Steelers vs. Bills predictions and picks
Browns vs. Chiefs
BET: Browns +5.5 with TwinSpires (-110)
📈 57% probability
The Chiefs look set to be in contention once again but another AFC team that is likely to be there at the pointy end of the season is the Browns.
Cleveland took a big step last season, making the playoffs and winning a postseason game against the Steelers. Now, with some defensive additions and Odell Beckham Jr. back from injury, they'll be keen to take it a step or two further.
DimersBOT rates the Browns as a 57% chance of covering the spread here, and they're also worth a little sprinkle at the moneyline.
MORE: Browns vs. Chiefs predictions and picks
Bears vs. Rams
BET: Bears +8 with TwinSpires (-110)
📈 56% probability
This pick is thanks to the one and only, DimersBOT, who has the Bears as a 56% chance of covering the spread in their season opener.
As it stands, the experienced Andy Dalton will be the starter for Week 1, and model likes that with the Bears facing the challenge of taking on Aaron Donald and his defensive line.
The Rams should be the much better team out of these two this season, but when it comes to Week 1, the underdogs look good to cover.
MORE: Bears vs. Rams predictions and picks
Your game not here? Find out who we're betting on for every NFL game on Sunday via our NFL Bet Hub, where we deliver you NFL predictions and suggested bets.
NFL Parlay For Sunday September 12, 2021
🔥 Bills -6.5
🔥 Browns +5.5
🔥 Bears +8
Parlay Odds +598
NFL 2021 Week 1 Schedule
Thursday September 9, 2021
Sunday September 12, 2021
- Philadelphia Eagles at Atlanta Falcons, 1PM ET
- Pittsburgh Steelers at Buffalo Bills, 1PM ET
- New York Jets at Carolina Panthers, 1PM ET
- Minnesota Vikings at Cincinnati Bengals, 1PM ET
- San Francisco 49ers at Detroit Lions, 1PM ET
- Jacksonville Jaguars at Houston Texans, 1PM ET
- Seattle Seahawks at Indianapolis Colts, 1PM ET
- Arizona Cardinals at Tennessee Titans, 1PM ET
- Los Angeles Chargers at Washington Football Team, 1PM ET
- Cleveland Browns at Kansas City Chiefs, 4:25PM ET
- Miami Dolphins at New England Patriots, 4:25PM ET
- Green Bay Packers at New Orleans Saints, 4:25PM ET
- Denver Broncos at New York Giants, 4:25PM ET
- Chicago Bears at Los Angeles Rams, 8:20PM ET (Sunday Night Football)
Monday September 13, 2021
We've sourced and reviewed the Best 2021 NFL Sportsbook Promotions so you don't have to! Click in to see what the 'books are serving up!
Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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