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Best MLB Betting Picks and Parlay - Friday, October 7, 2022

The MLB Playoffs begin with the wildcard round today. Let's start off with a bang with some best bets.
It's Friday, October 7, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for sports bettors across the United States.
With our MLB best bets, probabilities, and odds featured each and every day, check out our best betting picks for Wednesday's MLB games below.
Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.
Not with DraftKings yet? Well, sign up now and you'll get access to the best new customer MLB offer available. It's a bet $5 and get $100 no matter what offer, so simply click ➡️ here ⬅️, or tap the yellow button below.
Best MLB Bets Today
Rays vs. Guardians, 12:07PM ET
The Guardians are one of the biggest surprises in the MLB this season, making the playoffs despite having one of the youngest rosters in the league. Their manager, Terry Francona, is no stranger however, and we're sure he'll have the young guys ready. Cleveland is at home here, and should feel confident after winning the regular season series 4-2. Shane Bieber is on the mound for the Guardians, facing the Rays' ace Shane McClanahan, who is just 3-3 in starts on the road this season. We think Cleveland's magic continues into Game One.
BET: Guardians ML (-120). with DraftKings Sportsbook. Click ➡️ here ⬅️ to place your bet.
⚾️ Rays vs. Guardians Predictions
📈 Betting preview: Rays vs. Guardians
Mariners vs. Blue Jays, 4:07PM ET
The Mariners ended the longest playoff drought in baseball, making the postseason for the first time since 2001. There will be some extra juice for Seattle in this one, and while it's their first postseason appearance, they'll be facing a pitcher in the same situation. Alek Manoah is on the mound for Toronto, making his first career playoff start. Being the team with nothing to lose can often be fuel in a spot like this, and Seattle will be feeling like underdogs that can use that mojo to their advantage. The Mariners went 5-2 against Toronto in the regular season, so they should be confident coming in, and we like their chances to steal Game One on the road.
BET: Mariners ML (+110). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.
⚾️ Mariners vs. Blue Jays Predictions
📈 Betting preview: Mariners vs. Blue Jays
Padres vs. Mets, 8:07PM ET
Much was made of the Mets' meltdown late in the regular season to lose the division, but after all the drama, they still find themselves hosting Game One against the San Diego Padres with their ace Max Scherzer on the mound. There aren't many pitchers in baseball I'd rather avoid in the postseason than Scherzer, and he should stabilize any nerves for New York with his poise on the hill. The Mets are 54-27 at home this season, and they rebounded from the Braves debacle by sweeping the Nationals in three games in two days to restore momentum. Trumpets will be blaring, and the Mets will have a great chance to win this game.
BET: Mets ML (-150). Place this bet with DraftKings Sportsbook ➡️ here ⬅️.
⚾️ Mets vs. Padres Predictions
📈 Betting preview: Mets vs. Padres
Your game not here? Find out who we're betting on for every baseball game on Wednesday via our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section.
Best MLB Parlay Today
There are numerous different ways you can wager on MLB games in 2022, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $100 no matter what promo to guarantee a big cash.
Here's how to do it.
First, create your DraftKings account ➡️ here ⬅️, then make your first deposit of at least $5. Use that $5 to place a parlay using the below plays. If the parlay hits, you get yourself a nice payout, plus that $100 bonus. If it doesn't hit, well you've still got $100 free from DraftKings just for betting on MLB. Win-win!
🔥 Guardians ML
🔥 Mariners ML
🔥 Mets ML
MORE: Wednesday's MLB Props and Parlay
*All odds and lines correct at time of publishing