Baltimore Ravens vs. Buffalo Bills updated prediction featuring Derrick Henry, James Cook [Week 1, 2025]

Dimers' latest NFL predictions are live for Buffalo Bills and Baltimore Ravens in Week 1, with our model giving the Ravens a 58% of winning against the Bills on Sunday.

This update builds on our early Bills-Ravens predictions, delivering renewed win probabilities, score projections, and TD predictions for Derrick Henry, James Cook, and more.

For the most accurate simulation-based insights—including spread and total picks, touchdown probabilities, and the full list of player props—head to our Ravens vs. Bills page.

What's changed? Baltimore vs. Buffalo updated predictions

Our NFL predictions model has been re-run with the newest available data, creating a clearer picture of how this Ravens vs. Bills matchup stacks up. Here are the updated forecasted:

• Straight Up Win Probabilities: Ravens 58%, Bills 42%
• Predicted Final Score: Ravens 25-23 Bills
• Spread: Ravens (-1) 55%, Bills (+1) 45%
• Total Points (50.5): Over 47%, Under 53%

As of September 5, 2025, these Ravens-Bills numbers reflect changes since our early-week simulation.

Anytime touchdown scorer predictions

New projections highlight the top candidates to find the end zone in Ravens-Bills on Sunday:

Baltimore Ravens

• Derrick Henry: 58.3% probability
• Mark Andrews: 29.9% probability
• Lamar Jackson: 27.1% probability

Buffalo Bills

• James Cook: 51.2% probability
• Josh Allen: 44.5% probability
• Keon Coleman: 26.2% probability

Ravens vs. Bills latest odds

The best current odds from the top sportsbooks in the US:

• Spread: Ravens -1 (-105), Bills +1 (-115)
• Moneyline: Ravens -116, Bills +105
• Total: Over/Under 50.5 (-112/-105)

Odds are correct at time of publication and are subject to change—track live updates via our NFL odds page.

Ravens vs. Bills Week 1 details

The NFL Week 1 matchup between the Bills and Ravens at Highmark Stadium is scheduled for September 7, 2025.

• Who: Baltimore Ravens vs. Buffalo Bills
• Date: Sunday, September 7, 2025
• Time: 8:20PM ET/5:20PM PT
• Venue: Highmark Stadium

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Conclusion

We predict the Ravens, with a 58% win probability, will likely beat the Bills in Week 1 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Ravens vs. Bills game, with human oversight maintaining high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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