Orioles vs. Blue Jays Prediction: Toronto Predicted to Win MLB Opening Day Matchup [3/27/2025]

MLB Opening Day action continues on Thursday at 3:07PM ET as the Baltimore Orioles take on the Toronto Blue Jays at Rogers Centre.

The Blue Jays will send José Berríos (0-0, 0.00 ERA) to the mound, up against Zach Eflin (0-0, 0.00 ERA) for the Orioles.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Blue Jays as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's Baltimore-Toronto game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Blue Jays with a win probability of 51% and the Orioles with 49%."

For further insights into Thursday's matchup, including best bets and picks, visit our interactive Orioles vs. Blue Jays predictions page.

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Orioles vs. Orioles Prediction: Who Will Win on MLB Opening Day?

Using innovative machine learning and data, we have simulated the outcome of Thursday's MLB matchup between the Orioles and Blue Jays 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Blue Jays a 51% chance of defeating the Orioles.

According to our model, the Blue Jays (+1.5) have a 63% chance of covering the run line, while the 8.5-run over/under has a 51% chance of going over.

Orioles vs. Blue Jays Odds [3/27/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Orioles	Blue Jays
Run Line	-1.5 (+165)	+1.5 (-192)
Moneyline	+100	-110
Total	o8.5 (-102)	u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Orioles vs. Blue Jays Picks and Best Bets

Our model's strongest edge in today's Orioles vs. Blue Jays matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Orioles vs. Blue Jays Game-Day Updates and Essential Details

Thursday's MLB game between the Blue Jays and Orioles at Rogers Centre is scheduled to commence at 3:07PM ET.

• Who: Baltimore Orioles vs. Toronto Blue Jays
• Date: Thursday, March 27, 2025
• Time: 3:07PM ET/12:07PM PT
• Venue: Rogers Centre

Dimers.com's comprehensive preview of Thursday's Orioles vs. Blue Jays matchup includes our prediction, picks and the latest betting odds.

Before making any Baltimore vs. Toronto picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Blue Jays, with a 51% win probability, will likely beat the Orioles on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Blue Jays insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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