Orioles vs. Mariners Prediction: Seattle Predicted to Win Thursday's MLB Matchup [6/5/2025]

The Seattle Mariners and Baltimore Orioles will meet in MLB action at T-Mobile Park on Thursday, starting at 3:40PM ET.

Bryan Woo (5-2, 2.82 ERA) will be the starting pitcher for the Mariners, pitting him against Zach Eflin (4-2, 4.46 ERA) for the Orioles.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Mariners as the most likely winner of today's game.

"Using the latest data, our experts simulated Thursday's Baltimore-Seattle game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Taking into account recent updates and various additional inputs, we forecast the Mariners with a win probability of 56% and the Orioles with 44%."

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Orioles vs. Mariners predictions page.

Mariners vs. Orioles Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Thursday's MLB game between the Orioles and Mariners 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Mariners a 56% chance of beating the Orioles.

According to our model, the Orioles (+1.5) have a 63% chance of covering the run line, while the 7.5-run over/under has a 51% chance of staying under.

Orioles vs. Mariners Odds [6/5/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Orioles	Mariners
Run Line	+1.5 (-170)	-1.5 (+145)
Moneyline	+132	-148
Total	o7.5 (+102)	u7.5 (-122)

All odds are correct at the time of publication and are subject to change.

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Orioles vs. Mariners Picks and Best Bets

Our model's biggest edge in today's Orioles vs. Mariners matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Orioles vs. Mariners Game-Day Updates and Essential Details

Thursday's MLB game between the Mariners and Orioles at T-Mobile Park is scheduled to commence at 3:40PM ET.

• Who: Baltimore Orioles vs. Seattle Mariners
• Date: Thursday, June 5, 2025
• Time: 3:40PM ET/12:40PM PT
• Venue: T-Mobile Park

Dimers.com's comprehensive preview of Thursday's Orioles vs. Mariners matchup includes our prediction, picks and the latest betting odds.

Before making any Baltimore vs. Seattle picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Mariners, with a 56% win probability, will likely beat the Orioles on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Mariners insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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