Orioles vs. Twins Prediction: Minnesota Predicted to Win Tuesday's MLB Matchup [5/6/2025]

MLB action continues on Tuesday at 7:40PM ET as the Baltimore Orioles lock horns with the Minnesota Twins at Target Field.

The Twins will have Pablo López (2-2, 2.25 ERA) as their starting pitcher, pitting him against Cade Povich (1-2, 5.16 ERA) for the Orioles.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Baltimore-Minnesota game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Twins with a win probability of 58%, compared to 42% for the Orioles."

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Orioles vs. Twins predictions page.

Twins vs. Orioles Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Tuesday's MLB game between the Orioles and Twins 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Twins a 58% chance of beating the Orioles.

According to our model, the Orioles (+1.5) have a 62% chance of covering the run line, while the 9-run over/under has a 55% chance of staying under.

Orioles vs. Twins Odds [5/6/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Orioles	Twins
Run Line	+1.5 (-142)	-1.5 (+125)
Moneyline	+145	-170
Total	o9 (-102)	u9 (-112)

All odds are correct at the time of publication and are subject to change.

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Orioles vs. Twins Picks and Best Bets

Our model's strongest edge in today's Orioles vs. Twins matchup is on the over/under.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Orioles vs. Twins Game-Day Updates and Essential Details

Tuesday's MLB game between the Twins and Orioles at Target Field is scheduled to start at 7:40PM ET.

• Who: Baltimore Orioles vs. Minnesota Twins
• Date: Tuesday, May 6, 2025
• Time: 7:40PM ET/4:40PM PT
• Venue: Target Field

Dimers.com's full preview of Tuesday's Orioles vs. Twins matchup includes our prediction, picks and the latest betting odds.

Before making any Baltimore vs. Minnesota picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Twins, with a 58% win probability, will likely beat the Orioles on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Twins insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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