Orioles vs. Red Sox prediction: Boston predicted to win Monday's MLB matchup [8/18/2025]

MLB action continues on Monday at 7:10PM ET as the Baltimore Orioles take on the Boston Red Sox at Fenway Park.

The Red Sox will start Dustin May (7-8, 4.67 ERA), pitting him against Trevor Rogers (5-2, 1.43 ERA) for the Orioles.

Based on updated simulation results, Dimers' advanced MLB model predicts the Red Sox as the most likely winner of today's game.

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Orioles vs. Red Sox predictions page.

Red Sox vs. Orioles prediction: Who will win, cover the run line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Monday's MLB matchup between the Orioles and Red Sox 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Red Sox a 53% chance of defeating the Orioles.

According to our model, the Orioles (+1.5) have a 64% chance of covering the run line, while the 8-run over/under has a 52% chance of going over.

Orioles vs. Red Sox odds [8/18/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Orioles	Red Sox
Run Line	+1.5 (-201)	-1.5 (+170)
Moneyline	+106	-122
Total	o8 (-106)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Orioles vs. Red Sox picks and best bets

Our model's biggest edge in today's Orioles vs. Red Sox matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

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Orioles vs. Red Sox game-day updates and essential details

Monday's MLB matchup between the Red Sox and Orioles at Fenway Park is scheduled to begin at 7:10PM ET.

• Who: Baltimore Orioles vs. Boston Red Sox
• Date: Monday, August 18, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Fenway Park

Dimers.com's in-depth preview of Monday's Orioles vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Orioles vs. Red Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Red Sox, with a 53% win probability, will likely beat the Orioles on Monday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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