Orioles vs. Red Sox Prediction: Boston Predicted to Win Friday's MLB Matchup [5/23/2025]

The Boston Red Sox will face the Baltimore Orioles in MLB action at Fenway Park on Friday, beginning at 7:10PM ET.

The Red Sox will send Brayan Bello (2-1, 4.02 ERA) to the mound, up against Charlie Morton (0-7, 7.68 ERA) for the Orioles.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) projects the Red Sox as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Baltimore-Boston game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Red Sox' chance of winning is 54%, while the Orioles' is 46%."

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Orioles vs. Red Sox predictions page.

Red Sox vs. Orioles Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Friday's MLB matchup between the Orioles and Red Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Red Sox a 54% chance of beating the Orioles.

According to our model, the Orioles (+1.5) have a 62% chance of covering the run line, while the 9.5-run over/under has a 55% chance of staying under.

Orioles vs. Red Sox Odds [5/23/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Orioles	Red Sox
Run Line	+1.5 (-170)	-1.5 (+155)
Moneyline	+114	-130
Total	o9.5 (-110)	u9.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Orioles vs. Red Sox Picks and Best Bets

Our model's strongest edge in today's Orioles vs. Red Sox matchup is on the run line.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Orioles vs. Red Sox Game-Day Updates and Essential Details

Friday's MLB game between the Red Sox and Orioles at Fenway Park is scheduled to commence at 7:10PM ET.

• Who: Baltimore Orioles vs. Boston Red Sox
• Date: Friday, May 23, 2025
• Time: 7:10PM ET/4:10PM PT
• Venue: Fenway Park

Dimers.com's in-depth preview of Friday's Orioles vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Baltimore vs. Boston picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
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Conclusion

We predict the Red Sox, with a 54% win probability, will likely beat the Orioles on Friday.

AI and automation have enhanced this article to quickly deliver accurate Orioles vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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