Auburn vs. Oklahoma prediction: Oklahoma favored to win in college football Week 4, 2025

Oklahoma will square off with Auburn in Week 4 college football action at Gaylord Family Oklahoma Memorial Stadium on Saturday, beginning at 3:30PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts Oklahoma as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Auburn vs. Oklahoma predictions page.

Auburn vs. Oklahoma prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the outcome of Auburn vs. Oklahoma 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Oklahoma a 67% chance of defeating Auburn. Our predicted final score has Oklahoma winning 27-21.

According to our model, the bookmakers have got it right, and Auburn and Oklahoma each have a 50% chance of covering the spread, while the 47.5-point over/under has a 55% chance of staying under.

Auburn vs. Oklahoma odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Auburn	Oklahoma
Spread	+6.5 (-105)	-6.5 (-114)
Moneyline	+200	-245
Total	o47.5 (-105)	u47.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Auburn vs. Oklahoma picks and best bets

Our model's strongest edge in today's Auburn vs. Oklahoma matchup is on the spread.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Auburn vs. Oklahoma game-day updates and essential details

Saturday's college football matchup between Oklahoma and Auburn at Gaylord Family Oklahoma Memorial Stadium is scheduled to start at 3:30PM ET.

• Who: Auburn vs. Oklahoma
• Date: Saturday, September 20, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Gaylord Family Oklahoma Memorial Stadium

Dimers' comprehensive preview of Saturday's Auburn vs. Oklahoma matchup includes our prediction, picks and the latest betting odds.

Before making any Auburn vs. Oklahoma picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Oklahoma, with a 67% win probability, will likely beat Auburn on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Auburn vs. Oklahoma insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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