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Atletico Madrid vs. Real Madrid prediction, odds, La Liga picks [9/27/2025]

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Written by Damien Souness

Get Atletico Madrid vs Real Madrid predictions for La Liga Saturday.

Atletico Madrid-Real Madrid Predictions and Game Preview.
Atletico Madrid vs. Real Madrid La Liga prediction for Saturday, September 27, 2025.

Atletico Madrid and Real Madrid are scheduled to meet in La Liga at Riyadh Air Metropolitano on Saturday, with kickoff at 10:15AM ET.

Based on the latest simulation results, Dimers' advanced La Liga model projects Real Madrid as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Atletico Madrid vs. Real Madrid predictions page.

Atletico Madrid vs. Real Madrid prediction: Who will win?

Using innovative machine learning and data, we have simulated the result of Saturday's La Liga match between Atletico Madrid and Real Madrid 10,000 times as part of our La Liga predictions coverage.

Our leading predictive model currently indicates a 34.7% chance of Atletico Madrid winning, a 40.2% chance for Real Madrid, and a 25.0% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 54% chance of going over, according to our model.

 

Atletico Madrid vs. Real Madrid odds

We have sourced the best La Liga odds in America for this game, which are listed here:

Moneyline

Atletico Madrid Real Madrid Draw
+215 +125 +250

Total Goals

Over 2.5 Under 2.5
-140 +114

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Atletico Madrid vs. Real Madrid picks and best bets

Our model's biggest edge in today's Atletico Madrid vs. Real Madrid matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best La Liga picks and La Liga best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Atletico Madrid vs. Real Madrid: Correct score and BTTS predictions

Here are the top three most likely final scores according to our model, with a 1-1 draw being the most probable:

Final Score Probability
ATM 1-1 MAD 11.8%
ATM 1-2 MAD 8.7%
ATM 0-1 MAD 8.6%

When it comes to the both teams to score (BTTS) market, we project a 57.5% chance that both teams scoring, and a 42.5% probability of at least one team being held goalless.

These predictions are based on each team's average score after 10,000 simulations, which means the most likely correct score can differ from our predicted winner.

Atletico Madrid vs. Real Madrid game-day updates and essential details

Saturday's La Liga action between Atletico Madrid and Real Madrid at Riyadh Air Metropolitano is scheduled to begin in the United States at 10:15AM ET.

  • Who: Atletico Madrid vs. Real Madrid
  • Date: Saturday, September 27, 2025
  • Time: 10:15AM ET/7:15AM PT
  • Venue: Riyadh Air Metropolitano

Dimers' comprehensive preview of Saturday's Atletico Madrid vs. Real Madrid matchup includes our prediction, picks and the latest betting odds.

Before making any Real Madrid vs. Atletico Madrid picks, be sure to check out the latest La Liga predictions and betting advice from Dimers Pro.

Conclusion

According to our computer model, Atletico Madrid has a 34.7% win probability on Saturday, Real Madrid has a 40.2% win probability, and there is a 25.0% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Atletico Madrid vs. Real Madrid insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on La Liga

Keep up with the latest La Liga betting news and parlay picks throughout the season. Plus, our La Liga futures odds offer the latest probabilities for each La Liga title contender.

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Written by
Damien Souness
Chief Innovation Officer

Damien Souness leverages over 15 years of experience to create engaging content focused on sports, online gaming and wagering. As Chief Innovation Officer at Cipher Sports Technology Group, the parent company of Dimers, he offers strategic insights and innovative solutions to enhance the player experience.

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