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Atlas vs. Santos Laguna prediction, odds, Liga MX picks [9/13/2025]

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Written by Ryan Leaver

Get Atlas vs Santos Laguna predictions for Liga MX Saturday.

Atlas-Santos Laguna Predictions and Game Preview.
Atlas vs. Santos Laguna Liga MX prediction for Saturday, September 13, 2025.

Atlas will take on Santos Laguna in Liga MX action at Estadio Jalisco on Saturday, starting at 9:00PM ET.

Based on the latest simulation results, Dimers' advanced Liga MX model predicts Atlas as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Atlas vs. Santos Laguna predictions page.

Atlas vs. Santos Laguna prediction: Who will win?

Using innovative machine learning and data analysis, we have simulated the outcome of Saturday's Liga MX matchup between Atlas and Santos Laguna 10,000 times as part of our Liga MX predictions coverage.

Our leading predictive model suggests a 58.0% chance of Atlas winning, a 19.3% chance for Santos Laguna, and a 22.7% chance of a draw.

Additionally, the over/under total of 2.5 goals has a 53% chance of going over, according to our model.

 

Atlas vs. Santos Laguna odds

We have sourced the best Liga MX odds in America for this game, which are listed here:

Moneyline

Atlas Santos Laguna Draw
-110 +320 +270

Total Goals

Over 2.5 Under 2.5
-140 +114

All odds are correct at the time of publication and are subject to change.

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Atlas vs. Santos Laguna picks and best bets

Our model's strongest edge in today's Atlas vs. Santos Laguna matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best Liga MX picks and Liga MX best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Atlas vs. Santos Laguna: Correct score and BTTS predictions

The top three most likely final scores, according to our model, are listed below, with a 1-0 Atlas win being the most probable:

Final Score Probability
ATS 1-0 SLA 11.4%
ATS 1-1 SLA 10.8%
ATS 2-0 SLA 10.4%

When it comes to the both teams to score (BTTS) market, we project a 51.5% chance of the yes hitting, and a 48.5% probability of at least one team keeping a clean sheet.

These predictions are based on each team's average score after 10,000 simulations.

Atlas vs. Santos Laguna game-day updates and essential details

Saturday's matchup between Atlas and Santos Laguna at Estadio Jalisco is scheduled to begin at 9:00PM ET.

  • Who: Atlas vs. Santos Laguna
  • Date: Saturday, September 13, 2025
  • Time: 9:00PM ET/6:00PM PT
  • Venue: Estadio Jalisco

Dimers' full preview of Saturday's Atlas vs. Santos Laguna matchup includes our prediction, picks and the latest betting odds.

Before making any Santos Laguna vs. Atlas picks, be sure to check out the latest Liga MX predictions and betting advice from Dimers Pro.

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Conclusion

According to our computer model, Atlas has a 58.0% win probability on Saturday, Santos Laguna has a 19.3% win probability, and there is a 22.7% chance that the game will end in a draw.

AI and automation have enhanced this article to quickly deliver accurate Atlas vs. Santos Laguna insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on Liga MX

Keep up with the latest Liga MX news and parlay picks throughout the season.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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