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Braves vs. Nationals Prediction: Atlanta Predicted to Win Wednesday's MLB Matchup [5/21/2025]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Our expert prediction for Wednesday's Atlanta Braves vs Washington Nationals matchup.
The Washington Nationals and Atlanta Braves will lock horns in MLB action at Nationals Park on Wednesday, starting at 6:45PM ET.
The Nationals will have Trevor Williams (2-5, 5.91 ERA) as their starting pitcher, pitting him against AJ Smith-Shawver (3-2, 2.33 ERA) for the Braves.
Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Braves as the most likely winner of today's game.
"Our team has simulated the outcome of Wednesday's Atlanta-Washington game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"With the latest updates and numerous other variables, we estimate the Braves' chance of winning at 57%, with the Nationals at 43%."
For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Braves vs. Nationals predictions page.
Nationals vs. Braves Prediction: Who Will Win, Cover the Run Line?
Using powerful machine learning and data, we have simulated the result of Wednesday's MLB game between the Braves and Nationals 10,000 times as part of our MLB predictions coverage.
Our independent predictive model currently gives the Braves a 57% chance of defeating the Nationals.
According to our model, the Nationals (+1.5) have a 56% chance of covering the run line, while the 8.5-run over/under has a 51% chance of going over.
Braves vs. Nationals Odds [5/21/2025]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Braves | Nationals |
|---|---|---|
| Run Line | -1.5 (+110) | +1.5 (-125) |
| Moneyline | -154 | +130 |
| Total | o8.5 (-108) | u8.5 (-108) |
All odds are correct at the time of publication and are subject to change.
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Braves vs. Nationals Picks and Best Bets
Our model's strongest edge in today's Braves vs. Nationals matchup is on the total.
Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Free MLB Picks
Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.
Braves vs. Nationals Game-Day Updates and Essential Details
Wednesday's MLB matchup between the Nationals and Braves at Nationals Park is scheduled to begin at 6:45PM ET.
- Who: Atlanta Braves vs. Washington Nationals
- Date: Wednesday, May 21, 2025
- Time: 6:45PM ET/3:45PM PT
- Venue: Nationals Park
Dimers.com's full preview of Wednesday's Braves vs. Nationals matchup includes our prediction, picks and the latest betting odds.
Before making any Atlanta vs. Washington picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
- Understand where sports odds come from and how they're applied to baseball matchups
- Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
- Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on
Conclusion
We predict the Braves, with a 57% win probability, will likely beat the Nationals on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Braves vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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More on MLB
Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds provide the latest predictions for the World Series, American League, National League and each division.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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