Astros vs. Yankees Computer Picks, MLB Odds and Betting Lines for October 22, 2022

The desperate Yankees seek a win as the series heads to New York in a critical Game 3 of the ALCS. Once again, we have some best bets.

It's Saturday, October 22, 2022, and, as always, we've simulated all of the day's MLB games 10,000 times each to determine where the value lies for sports bettors across the United States.

With our MLB best bets, probabilities, and odds featured each and every day, check out our best betting picks for Wednesday's MLB games below.

Today's best MLB prop bets and odds are proudly brought to you by DraftKings Sportsbook.

If you’re looking to bet on baseball, then you should consider signing up with DraftKings ➡️ here ⬅️ where you can turn a $5 moneyline bet on any game into a free $200 instantly if it hits. You know you’ll be on the couch watching the games anyway, so why not take this free money from one of the best sportsbooks on the planet?

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Best MLB Bet Today

Yankees vs. Astros, 7:37PM ET

The Yankees bats have been quiet but their mouths haven't exactly followed suit. Aaron Boone and Luis Severino both made sure to complain that the roof wasn't closed in Houston, and that they deserved to win the game if it was. The larger issue for New York is that the Astros remain undefeated in the playoffs.

But the Yankees have the talent to keep up, and today they turn to their ace Gerrit Cole to save their season. Cole is 2-0 in the playoffs, pitching deep into both games and allowing just three runs in 13.1 innings pitched. It's the perfect formula for this series to tighten up, so we're rocking with the pinstripes.

BET: Yankees Moneyline (-140). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

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Best MLB Prop Today

The best hitter in baseball has had a slow start this series, but as mentioned, he has hit a few balls hard and far and come up with unlucky results. Judge homered twice in the Guardians series and it's only a matter of time before he hits a bomb in the ALCS. With the short porch at home, we see Judge getting very comfortable in Game 3, and leading the Yankees to the finish.

BET: Aaron Judge 1+ HR (+190). Want to tail this pick? Do it with DraftKings Sportsbook and get a nice bonus while doing so by clicking ➡️ here ⬅️.

⚾️ Yankees vs. Astros Predictions
✍🏼 Betting Preview: Yankees vs. Astros

Visit our MLB Bet Hub, where we deliver you MLB predictions and suggested bets, or check out the MLB Betting News section.

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Best MLB Same Game Parlay Today

There are numerous different ways you can wager on MLB games in 2022, such as the moneyline, run line, total, player and team props (strikeouts, RBIs, and home runs), and, of course, parlays. Given the high-risk, high reward nature of parlays, we're going to use the DraftKings Bet $5, win $200 no matter what promo to guarantee a big cash.

Here's how to do it.

First, create your DraftKings account ➡️ here ⬅️, then make your first deposit of at least $5. Use that $5 to place a parlay using the below plays. If the parlay hits, you get yourself a nice payout, plus that $200 bonus. If it doesn't hit, well you've still got $200 free from DraftKings just for betting on MLB. Win-win!

🔥 Yankees Moneyline
🔥 Judge HR

*All odds and lines correct at time of publishing