Aryna Sabalenka vs. Marketa Vondrousova prediction, odds, picks for US Open 2025

Aryna Sabalenka and Marketa Vondrousova will lock horns in the quarterfinals of the US Open 2025 on Tuesday.

Based on the latest simulations, Dimers' proven tennis model predicts Aryna Sabalenka as the most likely winner of the match.

For a closer look at Tuesday's match, including best bets and picks, visit our interactive Sabalenka vs. Vondrousova predictions page.

Sabalenka vs. Vondrousova prediction: Who will win and advance to the semifinals?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's Sabalenka-Vondrousova women's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model gives Sabalenka a 73% chance of beating Vondrousova in the US Open 2025.

Additionally, Sabalenka has a 69% chance of winning the first set, while the under 21.5 games has a 51% chance of hitting, according to our model.

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Aryna Sabalenka vs. Marketa Vondrousova odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Sabalenka	Vondrousova
Moneyline	-285	+250
First Set	-227	+175
Total Games	o21.5 (-110)	u21.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Sabalenka vs. Vondrousova picks and best bets

Our model's biggest edge in the Sabalenka vs. Vondrousova match is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Sabalenka vs. Vondrousova updates and essential details

The US Open 2025 match between Aryna Sabalenka and Marketa Vondrousova is scheduled to commence on Tuesday at 7:00PM ET.

• Who: Aryna Sabalenka vs. Marketa Vondrousova
• Date: Tuesday, September 2, 2025
• Approx. Time: 7:00PM ET/4:00PM PT
• Tournament: US Open Women's Singles 2025
• Round: Quarterfinals

All dates and times in this article are United States Eastern Time unless otherwise noted.

Dimers.com's comprehensive preview of Tuesday's Sabalenka vs. Vondrousova match includes our prediction, picks and the latest betting odds.

Before making any Aryna Sabalenka vs. Marketa Vondrousova picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Aryna Sabalenka, with a 73% win probability, will likely beat Marketa Vondrousova at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Sabalenka vs. Vondrousova insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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