Aryna Sabalenka vs. Amanda Anisimova prediction, odds, picks for US Open 2025

Aryna Sabalenka and Amanda Anisimova will meet in the final of the US Open 2025 on Saturday.

Based on updated simulation results, Dimers' advanced tennis model predicts Aryna Sabalenka as the most likely winner of the match.

For further insights into Saturday's match, including best bets and picks, visit our interactive Sabalenka vs. Anisimova predictions page.

Sabalenka vs. Anisimova prediction: Who will win the final?

Using trusted machine learning and data analysis, we have simulated the outcome of Saturday's Sabalenka-Anisimova women's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model currently gives Sabalenka a 63% chance of defeating Anisimova in the US Open 2025.

Additionally, Sabalenka has a 61% chance of winning the first set, while the under 22.5 games has a 54% chance of hitting, according to our model.

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Aryna Sabalenka vs. Amanda Anisimova odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Sabalenka	Anisimova
Moneyline	-175	+175
First Set	-164	+130
Total Games	o22.5 (-110)	u22.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Sabalenka vs. Anisimova picks and best bets

Our model's biggest edge in today's Sabalenka vs. Anisimova match is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best tennis picks and tennis best bets for every match throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Sabalenka vs. Anisimova updates and essential details

The US Open 2025 match between Aryna Sabalenka and Amanda Anisimova is scheduled to start on Saturday at 4:00PM ET.

• Who: Aryna Sabalenka vs. Amanda Anisimova
• Date: Saturday, September 6, 2025
• Approx. Time: 4:00PM ET/1:00PM PT
• Tournament: US Open Women's Singles 2025
• Round: Final

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Dimers.com's comprehensive preview of Saturday's Sabalenka vs. Anisimova match includes our prediction, picks and the latest betting odds.

Before making any Aryna Sabalenka vs. Amanda Anisimova picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
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Conclusion

We predict Aryna Sabalenka, with a 63% win probability, will likely beat Amanda Anisimova at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Sabalenka vs. Anisimova insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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