MLB- More Betting
Diamondbacks vs. Giants Prediction: Arizona Predicted to Win Monday's MLB Matchup [5/12/2025]
Our expert prediction for Monday's Arizona Diamondbacks vs San Francisco Giants matchup.

The San Francisco Giants and Arizona dbacks will lock horns in MLB action at Oracle Park on Monday, starting at 9:45PM ET.
The Giants will have Justin Verlander (0-2, 4.50 ERA) as their starting pitcher, while the Diamondbacks will counter with Merrill Kelly (3-2, 4.09 ERA).
Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.
"Our team has utilized the latest data to simulate Monday's Arizona-San Francisco game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.
"Incorporating recent updates and thousands of additional inputs, our prediction shows the Diamondbacks are likely to win, with a probability of 53%, compared to the Giants' 47%."
For a closer look at Monday's matchup, including best bets and picks, visit our interactive Diamondbacks vs. Giants predictions page.
Giants vs. Diamondbacks Prediction: Who Will Win, Cover the Run Line?
Using trusted machine learning and data analysis, we have simulated the result of Monday's MLB game between the Diamondbacks and Giants 10,000 times as part of our MLB predictions coverage.
Our leading predictive model currently gives the Diamondbacks a 53% chance of beating the Giants.
According to our model, the Giants (+1.5) have a 61% chance of covering the run line, while the over/under total of 8 runs has an equal 50-50 chance of hitting.
Diamondbacks vs. Giants Odds [5/12/2025]
We have researched the best MLB odds in America for this game, which are listed here:
Bet Type | Diamondbacks | Giants |
---|---|---|
Run Line | -1.5 (+150) | +1.5 (-164) |
Moneyline | -118 | +106 |
Total | o8 (-110) | u8 (-105) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Diamondbacks vs. Giants Picks and Best Bets
Our model's biggest edge in today's Diamondbacks vs. Giants matchup is on the moneyline.
Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.
Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.
Calling Our Shot's Best Bets Today
Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.
Diamondbacks vs. Giants Game-Day Updates and Essential Details
Monday's MLB game between the Giants and Diamondbacks at Oracle Park is scheduled to begin at 9:45PM ET.
- Who: Arizona Diamondbacks vs. San Francisco Giants
- Date: Monday, May 12, 2025
- Time: 9:45PM ET/6:45PM PT
- Venue: Oracle Park
Dimers.com's comprehensive preview of Monday's Diamondbacks vs. Giants matchup includes our prediction, picks and the latest betting odds.
Before making any Arizona vs. San Francisco picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.
Key MLB Betting Guides and Insights
- Explore how MLB odds work and dive into MLB live betting strategies
- Understand where sports odds come from and how they're applied to baseball matchups
- Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
- Stay informed with where online sports betting is currently legal and which betting sites are safest to use
- Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on
Conclusion
We predict the Diamondbacks, with a 53% win probability, will likely beat the Giants on Monday.
AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
More on MLB
Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.