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Diamondbacks vs. Padres Prediction: Arizona Predicted to Win Thursday's MLB Matchup [7/10/2025]

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Written by Dave Garofolo

Our expert prediction for Thursday's Arizona Diamondbacks vs San Diego Padres matchup.

Arizona Diamondbacks-San Diego Padres Predictions and Game Preview.
PETCO Park sets the stage for the MLB matchup between the Arizona Diamondbacks and San Diego Padres this Thursday.

MLB action continues on Thursday at 9:40PM ET as the Arizona Diamondbacks take on the San Diego Padres at PETCO Park.

Randy Vásquez (3-4, 3.79 ERA) will start for the Padres, pitting him against Eduardo Rodriguez (3-5, 5.78 ERA) for the Diamondbacks.

Based on updated simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Diamondbacks as the most likely winner of today's game.

For expanded analysis of Thursday's matchup, including best bets and picks, visit our interactive Diamondbacks vs. Padres predictions page.

Padres vs. Diamondbacks Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Thursday's MLB game between the Diamondbacks and Padres 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Diamondbacks a 52% chance of beating the Padres.

According to our model, the Padres (+1.5) have a 62% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

 

Diamondbacks vs. Padres Odds [7/10/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Diamondbacks Padres
Run Line -1.5 (+140) +1.5 (-164)
Moneyline -120 +106
Total o8.5 (-120) u8.5 (+100)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Diamondbacks vs. Padres Picks and Best Bets

Our model's biggest edge in today's Diamondbacks vs. Padres matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Diamondbacks vs. Padres Game-Day Updates and Essential Details

Thursday's MLB game between the Padres and Diamondbacks at PETCO Park is scheduled to start at 9:40PM ET.

Dimers.com's in-depth preview of Thursday's Diamondbacks vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Diamondbacks vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Diamondbacks, with a 52% win probability, will likely beat the Padres on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Diamondbacks vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds offer the most up-to-date probabilities for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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